Polyester based in situ forming implants (ISFIs) are injectable long-acting drug delivery systems that offer a wide range of unique advantages. As a result of these advantages, two relatively high molecular weight, ester terminated grades of poly (D,L-lactide-co-glycolide) (PLGA) and poly(D,L-lactide) (PLA) were evaluated for their ability (i) to form ISFIs loaded with carvedilol, and (ii) to control its release both in vitro and in vivo. At a polymeric concentration of 40% w/w, implant solutions were syringeable, injectable, and able to encapsulate carvedilol to a high degree (encapsulated drug% > 97%).
View Article and Find Full Text PDFAim: This study aims to evaluate the awareness and knowledge of ionizing radiation in common radiological investigations, as well as the associated risks, among medical and applied medical sciences students at Majmaah University in Majmaah, Saudi Arabia.
Materials And Methods: This cross-sectional study involved 209 participants who completed an anonymous electronic questionnaire consisting of 21 questions. Participants were categorized based on demographic characteristics and assessed for their awareness and knowledge of radiation and its associated risks.