Publications by authors named "M A Al Mofarreh"
Background: The role of microbiota in the pathogenesis of ulcerative colitis (UC) has been increasingly recognized. However, most of the reports are from Western populations. In Middle Eastern countries, including Saudi Arabia, little is known about the role of microbiota.
View Article and Find Full Text PDFBackground: Intestinal dysbiosis has been reported to be associated with celiac disease (CeD) in Western populations but little is known in other populations who have different dietary lifestyle and genetic background. The purpose of this study was to determine whether a different microbiota profile is associated with CeD in children in Saudi Arabia.
Results: Forty children with CeD, 20 healthy controls, and 19 non-CeD controls were enrolled.
Article Synopsis
- * This study analyzed the viral profiles from fecal and mucosal samples of 40 children with new-onset CeD and 39 healthy controls, finding distinct viral dysbiosis in the CeD group.
- * Although specific viral species were found to be more or less abundant in the fecal samples of children with CeD, mucosal samples did not show significant associations, highlighting the complexity of viral interactions in gut health and the need for more research.
Background: Although intestinal fungi are known to interact with the immune system, the relationship between intestinal fungi and childhood celiac disease (CeD), an immune-mediated condition, has rarely been reported.
Aims: The aim of this study was to describe gut fungal profiles in a cohort of children with new-onset CeD.
Methods: Mucosal and fecal samples were collected from children with CeD and controls and subjected to metagenomics analysis of fungal microbiota communities.
Background/aim: Delay in the diagnosis of inflammatory bowel disease (IBD) is associated with complications. Our aim was to describe the pattern and risk factors associated with delay in the diagnosis of IBD in Saudi children.
Patients And Methods: This was a multicenter study with a retrospective/prospective design.