Publications by authors named "M A Adeniyi"
The impact of artificial light exposure on human health has garnered significant attention in recent years. In particular, its effects on reproductive health have raised concerns. Given that the onset of menarche serves as a crucial indicator of reproductive maturity, understanding the implications of artificial light exposure becomes paramount.
View Article and Find Full Text PDFBackground Investigating changes in brain electroencephalogram activity during blood pressure measurement in sitting and standing positions is clinically significant for understanding the neural correlates of postural changes, which may affect cerebral perfusion and autonomic regulation. Shifts in blood pressure can influence visual cortical activity, potentially altering cognitive and sensory processing. This research holds clinical relevance in evaluating disorders like orthostatic hypotension and syncope, where postural changes compromise cerebral blood flow.
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- * A new liquid chromatography-mass spectrometry (LC-MS) method was developed to effectively profile gangliosides, optimizing both the extraction and analysis processes for better accuracy and recovery.
- * This study found that the ganglioside profiles vary significantly across different cancer cell lines, indicating the potential of the method for identifying specific lipid markers related to cancer types.
Article Synopsis
- Glyphosate, a common herbicide since the 1970s, has raised health concerns despite initial beliefs of its safety due to the absence of a specific biological pathway in humans and animals.
- The study investigated changes in -glycosylation, a post-translational modification of proteins, in rats exposed to glyphosate-based herbicides, utilizing advanced techniques like LC-MS/MS for analysis.
- Findings indicated significant alterations in the -glycan profile of rat serum, with male rats showing more susceptibility to changes than females, suggesting potential neurological implications and enhancing understanding of glyphosate's toxic effects.
The neurological condition known as narcolepsy type 1 (NT1) is an uncommon condition marked by extreme daytime sleepiness, cataplexy, sleep paralysis, hallucinations, disrupted nocturnal sleep, and low or undetectable levels of orexin in the CSF fluid. NT1 has been hypothesized to be an immunological disorder; its treatment is currently only symptomatic, and misdiagnosis is not uncommon. This study compares the -glycome of NT1 patients with healthy controls in search of potential glycan biomarkers using LC-MS/MS.
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