Publications by authors named "Lysikova T"

Article Synopsis
  • * The study identified 22 proteins with altered levels in heart homogenates of rats with chronic mild HHcy, highlighting their roles in energy metabolism, cardiac function, stress response, and antioxidant defense.
  • * Findings showed decreased antioxidant defenses and increased oxidative damage, suggesting that both altered protein expression and oxidative stress contribute to heart damage in HHcy.
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It is well known that the brain is quite vulnerable to oxidative stress, initiating neuronal loss after ischemia-reperfusion (IR) injury. A potent protective mechanism is ischemic preconditioning (IPC), where proteins are among the primary targets. This study explores redox-active proteins' role in preserving energy supply.

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During aging, heart structure and function gradually deteriorate, which subsequently increases susceptibility to ischemia-reperfusion (IR). Maintenance of Ca homeostasis is critical for cardiac contractility. We used Langendorff's model to monitor the susceptibility of aging (6-, 15-, and 24-month-old) hearts to IR, with a specific focus on Ca-handling proteins.

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To alleviate neurological complications (extrapyramidal and hypothalamic syndromes, polyneuropathies and polyneuritis) associated with chronic alcoholism, 227 patients received different variants of acupuncture (classical acupuncture with needles, electropuncture, laser puncture). During the first three days, to control the abstinence syndrome, all patients received classical acupuncture. Further application of one or another method of acupuncture was determined by the degree of neurological complications.

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