Publications by authors named "Lyra S"

Electrical Impedance Tomography (EIT) is a cost-effective and fast way to visualize dielectric properties of the human body, through the injection of alternating currents and measurement of the resulting potential on the bodies surface. However, this comes at the cost of low resolution as EIT is a non-linear ill-posed inverse problem. Recently Deep Learning methods have gained the interest in this field, as they provide a way to mimic non-linear functions.

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Neonatal sepsis is one of the most serious complications in neonatal intensive care units. Due to the often immature immune system, sepsis-related comorbidities are the major contributors to increased neonatal mortality. The rapid progression of the disease makes early treatment critical for patient survival.

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Preterm infants are at an increased health risk due to their low maturity. To monitor their health, vital signs are measured using contact-based methods. The adhesive sensors used to detect body temperature can damage the sensitive skin of neonates.

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Cardiorespiratory coordination (CRC) probes the interaction between cardiac and respiratory oscillators in which cardiac and respiratory activity are synchronized, with individual heartbeats occurring at approximately the same temporal positions during several breathing cycles. An increase of CRC has previously been related to pathological stressful states. We studied CRC employing coordigrams computed from non-contact photoplethysmography imaging (PPGI) and respiratory data using the optical flow method.

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Background: Monitoring the body temperature of premature infants is vital, as it allows optimal temperature control and may provide early warning signs for severe diseases such as sepsis. Thermography may be a non-contact and wireless alternative to state-of-the-art, cable-based methods. For monitoring use in clinical practice, automatic segmentation of the different body regions is necessary due to the movement of the infant.

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In today's neonatal intensive care units, monitoring vital signs such as heart rate and respiration is fundamental for neonatal care. However, the attached sensors and electrodes restrict movement and can cause medical-adhesive-related skin injuries due to the immature skin of preterm infants, which may lead to serious complications. Thus, unobtrusive camera-based monitoring techniques in combination with image processing algorithms based on deep learning have the potential to allow cable-free vital signs measurements.

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The continuous monitoring of vital signs is a crucial aspect of medical care in neonatal intensive care units. Since cable-based sensors pose a potential risk for the immature skin of preterm infants, unobtrusive monitoring techniques using camera systems are increasingly investigated. The combination of deep learning-based algorithms and camera modalities such as RGB and infrared thermography can improve the development of cable-free methods for the extraction of vital parameters.

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Distributed cutaneous tissue blood volume oscillations contain information on autonomic nervous system (ANS) regulation of cardiorespiratory activity as well as dominating thermoregulation. ANS associated with low-frequency oscillations can be quantified in terms of frequencies, amplitudes, and phase shifts. The relative order between these faculties may be disturbed by conditions colloquially termed 'stress'.

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Premature infants are among the most vulnerable patients in a hospital. Due to numerous complications associated with immaturity, a continuous monitoring of vital signs with a high sensitivity and accuracy is required. Today, wired sensors are attached to the patient's skin.

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Neonatal intensive care units provide vital medical support for premature infants. The key aspect in neonatal care is the continuous monitoring of vital signs measured using adhesive skin sensors. Since sensors can cause irritation of the skin and lead to infections, research focuses on contact-free, camera-based methods such as infrared thermography and photoplethysmography imaging.

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DivulgaMicro is a Brazilian science communication and outreach project run by three young female scientists. In 2020, due to the COVID-19 pandemic, we promoted the first virtual edition of the DivulgaMicro Workshop. Here, we describe adaptations implemented to deliver the virtual edition and its assessment by the participants.

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Infrared thermography for camera-based skin temperature measurement is increasingly used in medical practice, e.g., to detect fevers and infections, such as recently in the COVID-19 pandemic.

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Ventricular Assist Devices (VADs) are used to treat patients with cardiogenic shock. As the heart is unable to supply the organs with sufficient oxygenated blood and nutrients, a VAD maintains the circulation to keep the patient alive. The observation of the patient's hemodynamics is crucial for an individual treatment; therefore, sensors to measure quantifiable hemodynmaic parameters are desirable.

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Photoplethysmography imaging (PPGI) for non-contact monitoring of preterm infants in the neonatal intensive care unit (NICU) is a promising technology, as it could reduce medical adhesive-related skin injuries and associated complications. For practical implementations of PPGI, a region of interest has to be detected automatically in real time. As the neonates' body proportions differ significantly from adults, existing approaches may not be used in a straightforward way, and color-based skin detection requires RGB data, thus prohibiting the use of less-intrusive near-infrared (NIR) acquisition.

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Objective: Photoplethysmography imaging (PPGI) is a promising contactless camera-based method of non-invasive cardiovascular diagnostics. To achieve the best results, it is important to choose the most suitable camera for a specific application. The settings of the camera influence the quality of the detected signal.

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Objective: Acute ischemic stroke and silent cerebral infarctions following pipeline embolization device (PED) treatment of intracranial aneurysms have been estimated to occur in 3-6% and in 50.9-90% of patients respectively. The PED with Shield technology (PED-Shield) incorporates a surface phosphorylcholine polymer to reduce the thrombogenicity of the implant.

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Objectives: Camera-based vital sign estimation allows the contactless assessment of important physiological parameters. Seminal contributions were made in the 1930s, 1980s, and 2000s, and the speed of development seems ever increasing. In this suivey, we aim to overview the most recent works in this area, describe their common features as well as shortcomings, and highlight interesting "outliers".

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Article Synopsis
  • Evidence suggests that insecticide-treated bed nets (ITNs) and indoor spraying have changed mosquito biting and resting behavior, impacting malaria control efforts.
  • An agent-based model simulates how ITNs affect mosquito fitness by altering biting rates and increasing mortality, factoring in genetic adaptability to aid in survival.
  • Results reveal that certain mosquito strains are evolving to bite earlier when ITN coverage is around 50%, suggesting a significant effect of ITNs on mosquito behavior and fitness dynamics.
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Background And Importance: This case highlights the fact that acute pituitary apoplexy may be misdiagnosed due to being confused with other entities exhibiting similar symptoms, such as meningitis or subarachnoid hemorrhage.

Clinical Presentation: A patient in his late 30s presented with sudden and severe frontal headache, fever, blurred vision, nausea, confusion, as well as oculomotor palsy (CN III) with partial ptosis of the left eyelid, dilated left pupil and left eye globe deviation inferiorly and laterally. The final diagnosis was acute pituitary apoplexy complicating a pituitary macroadenoma.

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Background: Magnetotactic bacteria (MTB) are a unique group of prokaryotes that have a potentially high impact on global geochemical cycling of significant primary elements because of their metabolic plasticity and the ability to biomineralize iron-rich magnetic particles called magnetosomes. Understanding the genetic composition of the few cultivated MTB along with the unique morphological features of this group of bacteria may provide an important framework for discerning their potential biogeochemical roles in natural environments.

Results: Genomic and ultrastructural analyses were combined to characterize the cultivated magnetotactic coccus Magnetofaba australis strain IT-1.

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Unlabelled: Pituitary abscess is a rare life-threating entity that is usually misdiagnosed as a pituitary tumor with a definite diagnosis only made postoperatively. Over the last several decades, advances in healthcare have led to a significant decrease in morbidity and mortality due to pituitary abscess. We report a case of a 34-year-old woman who was admitted to our department for investigation of a pituitary mass and with symptoms of pituitary dysfunction, headaches and impaired vision.

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To examine, if case series considered together with observational studies tend to produce similar results as randomized-controlled trials (RCTs), on recurrent hernia repair. A systematic literature review and meta-analysis between 1990 and 2013 revealed 46 nonrandomized studies (NRCTs) and 5 RCTs including 25,730 patients. A direct comparison of the summary estimates between RCTs and NRCTs is presented.

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Background: We sought to investigate the incidence and location of new cerebral ischemic lesions after carotid endarterectomy (CEA) using diffusion-weighted magnetic resonance imaging (DW-MRI).

Methods: Sixty-six consecutive patients (50 males with a mean [±SD] age of 69 ± 9 years) who underwent CEA were included in this prospective study. Seventeen patients were symptomatic and 49 patients were asymptomatic.

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Background: Demyelinating diseases cause destruction of the myelin sheath, while axons are relatively spared. Pathologically, demyelination can be the result of an inflammatory process, viral infection, acquired metabolic derangement and ischemic insult. Three diseases that can cause inflammatory demyelination of the CNS are: Multiple sclerosis (MS), Acute disseminated encephalomyelitis (ADEM) and Acute hemorrhagic leucoencephalitis.

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