Simplifying the preevacuation testing strategy for patients with molar pregnancy.

Objective: To review our institution's preevacuation testing strategy for suspected molar pregnancy to determine whether a simplified approach might be indicated.

Study Design: Patients diagnosed with molar pregnancy from 1999 to 2004 were identified. Clinical data were retrospectively extracted from medical records.

Proteomic biomarker identification for diagnosis of early relapse in ovarian cancer.

Ovarian cancer recurs at the rate of 75% within a few months or several years later after therapy. Early recurrence, though responding better to treatment, is difficult to detect. Surface-enhanced laser desorption/ionization time-of-flight (SELDI-TOF) mass spectrometry has showed the potential to accurately identify disease biomarkers to help early diagnosis.

Diagnosis of early relapse in ovarian cancer using serum proteomic profiling.

Surface-enhanced laser desorption/ionization time-of-flight (SELDI-TOF) mass spectrometry data has been increasingly analyzed for identifying biomarkers to help early detection of the disease. Ovarian cancer commonly recurs at the rate of 75% within a few months or several years later after standard treatment. Since recurrent ovarian cancer is relatively difficult to be diagnosed and small tumors generally respond better to treatment, new methods for the detection of early relapse in ovarian cancer are urgently needed.

Retrospective cohort study of surgical staging for ovarian low malignant potential tumors.

Objective: The purpose of this study was to determine the benefit of surgically staging ovarian low malignant potential tumors.

Study Design: This was a retrospective cohort study of all ovarian low malignant potential tumors that were diagnosed by frozen section or final pathologic review from 2003 to 2005.

Results: Twenty-two of 32 patients (69%) were staged surgically.

Adenocarcinoma of the cervix.

Cervical adenocarcinomas are increasing in incidence each year, comprising up to 25% of all cervical cancers diagnosed in the United States. This increase largely reflects the inherent difficulty in detecting glandular precursor lesions using current screening practices. However, there also appears to be a recent shift in the epidemiology of the disease process with younger women being diagnosed more frequently.