Publications by authors named "Lynne Dixon"
Article Synopsis
- There is growing interest in hypofractionated radiotherapy for head and neck cancer, but not enough data to establish a consensus on its use.
- This multicenter study examined outcomes in oropharyngeal squamous cell carcinoma patients treated with either standard or accelerated mildly hypofractionated radiotherapy without chemotherapy.
- Results showed no significant differences in locoregional control, overall survival, or swallowing function between the two treatment schedules, suggesting hypofractionated radiotherapy is a viable option for patients who cannot receive chemotherapy.
Article Synopsis
- The study aimed to determine if the pretreatment absolute lymphocyte count (ALC) can help identify oropharyngeal squamous cell carcinoma (OPSCC) patients who might benefit from reducing chemotherapy during treatment.
- Researchers analyzed data from nearly 800 patients undergoing treatment, assessing overall survival (OS) and locoregional control (LRC) based on ALC levels.
- Findings suggested that ALC is a significant predictor of OS and indicates how well patients might respond to adding cisplatin chemotherapy, potentially guiding future treatment de-escalation strategies.
Article Synopsis
- * Seven clinicians tested their ability to outline these muscles on CT scans with and without the atlas, revealing that the atlas significantly improved agreement among clinicians.
- * Results showed that the atlas reduced variability in muscle contouring and could serve as a valuable educational resource for clinicians planning radiotherapy for head and neck cancer patients.
Article Synopsis
- The study investigates long-term swallowing outcomes in patients with oropharyngeal carcinoma who underwent chemoradiotherapy at two UK centers, aiming to gather patient-reported results and identify influencing factors.
- After excluding patients needing enteral feeding or those with disease relapse, 201 out of 242 eligible patients completed a swallowing inventory two years post-treatment, revealing a median score indicating varying degrees of swallowing function.
- Findings indicate that many patients experience long-term swallowing dysfunction, particularly those with poor pre-treatment diets or who required feeding tubes, highlighting the need for better management strategies in these groups.
Article Synopsis
- The study investigated the effects of hypofractionated accelerated radiotherapy on T2 glottic cancers, focusing on outcomes and late toxicity.
- It treated 112 patients with a specific dose regimen and reported a 67% overall survival rate and 82% local control after five years.
- The findings suggest that hypofractionated treatments improve local control while maintaining low levels of late toxicity, indicating they should be considered as standard care for early glottic laryngeal cancers.
Purpose: Palliative radiotherapy has traditionally been used as a noninvasive means of palliating dysphagia in patients with incurable esophageal cancer. Insertion of an esophageal stent is a traditional alternative and newer treatment modalities such as brachytherapy and laser therapy are being increasingly investigated and employed. There are few large series in the literature which examine the role of short palliative radiotherapy regimens in this patient group.
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- The case discusses a patient with metastatic non-small cell lung cancer who developed Clostridium septicum myonecrosis while undergoing palliative chemotherapy.
- This condition is a rare but significant possibility to consider when cancer patients experience sudden acute pain.
- Quick diagnosis and treatment are crucial, as the condition can lead to rapid decline and may be fatal without aggressive intervention.
Dear Editor, We read with interest the article "Aortic dissection: a review of the diagnosis and initial management" by Thompson-Moore and Papouchado1; the authors do not mention pleural effusion as a presenting x-ray feature of this condition. A case in our unit highlights the importance of considering aortic dissection for patients with unexplained haemothorax.
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