Effects of delta-9-tetrahydrocannabinol, the primary psychoactive cannabinoid in marijuana, on human sperm function in vitro.

Objective: To investigate effects of delta-9-tetrahydrocannabinol (THC) on human sperm function in vitro.

Design: Laboratory analysis of sperm motility after exposure to THC using computer-assisted semen analysis and acrosome reaction by fluoroscein isothiocyanate-labeled peanut agglutinin staining.

Setting: An assisted reproductive technology unit.