How Can I Feel Safe at Home? Adolescents' Experiences of Family Violence in Ghana.

Despite the implementation of various national legal frameworks and global policies such as the UN Convention on the Rights of the Child to combat violence against young people, family violence against young people is prevalent, especially in WHO African region. Although, research on child maltreatment, specifically, for young children has received considerable attention in Ghana recently, there is little research on adolescents' experiences of such family violence. In this paper, we report the experiences and perceptions of adolescents with respect to family violence they had suffered or witnessed, and analyze the socio-ecological factors and power dynamics at home that contribute to such violence.

The double hazard in recovery journey: The experiences of UK Chinese users of mental health services.

Background: The recent interest in recovery from mental health problems has not meaningfully addressed the perspectives of ethnic minorities.

Aim: To contribute to the discussion of recovery-oriented service with a study on the experience of Chinese people using UK mental health services.

Methods: In-depth life history interviews were carried out with the users.

The core and accessory genomes of Burkholderia pseudomallei: implications for human melioidosis.

Natural isolates of Burkholderia pseudomallei (Bp), the causative agent of melioidosis, can exhibit significant ecological flexibility that is likely reflective of a dynamic genome. Using whole-genome Bp microarrays, we examined patterns of gene presence and absence across 94 South East Asian strains isolated from a variety of clinical, environmental, or animal sources. 86% of the Bp K96243 reference genome was common to all the strains representing the Bp "core genome", comprising genes largely involved in essential functions (eg amino acid metabolism, protein translation).

Characterization of pyrazinamide and ofloxacin resistance among drug resistant Mycobacterium tuberculosis isolates from Singapore.

Objectives: To evaluate rapid molecular approaches for the detection of pyrazinamide (PZA) and ofloxacin resistance, by screening 100 known drug-resistant Mycobacterium tuberculosis isolates.

Methods: Mycobacterium tuberculosis isolates were tested for phenotypic resistance to pyrazinamide and ofloxacin using the BACTEC 460 radiometric method and the E-test, respectively. Mutation screening was done by amplifying the pncA, gyrA, and gyrB genes by the polymerase chain reaction (PCR) and direct automated sequencing.

Discrimination of single-copy IS6110 DNA fingerprints of Mycobacterium tuberculosis isolates by high-resolution minisatellite-based typing.

Seven isoniazid-resistant isolates with mutations in the NADH dehydrogenase (ndh) gene were molecularly typed by IS6110-based restriction fragment length polymorphism analysis. All seven isolates with the R268H mutation had identical 1.4-kb IS6110 fingerprints.