Nutritional status of home hemodialysis patients.

We studied the nutritional status of 32 patients (23 men), aged 50 (SD14) yr, on home hemodialysis (HHD) for one-138 months. No formal dietary restrictions were imposed. Anthropometric measurements were made using standard techniques, diet assessed by three-day dietetic diary and interview and plasma concentrations of nutrients were measured.

Increased skin temperature after vibratory stimulation.

The skin temperature effect of vibratory stimulation was studied in 28 healthy subjects. Vibration (50 Hz or 100 Hz) was applied to the volar surface of the left forearm for 15 min. Skin temperature of the bilateral forearms was measured before and immediately after cessation of vibration and at 5 and 10 min postvibration.

Gastrointestinal and systemic candidosis in immunocompromised mice.

Oral-intragastric inoculation of 6-day-old outbred Crl:CFW(SW) BR mice with Candida albicans can lead to colonization of the gastrointestinal (GI) tract. We have shown that in the absence of an immunocompromising treatment, Candida is primarily localized in the stomach and intestines of mice at 20 days post-inoculation. Cultures of homogenates of the esophagus of most animals tested, and homogenates of the liver, lungs, spleen and kidneys of all animals tested, proved negative for C.

Renal disease in diabetics--which patients have diabetic nephropathy and what is their outcome?

From August 1974 to January 1985, 53 patients (26 men; seven Maoris) mean age 45 (SD 15) years, with diabetes mellitus for a mean of 12 (SD nine) years had a renal biopsy and were followed. Indications for biopsy were nephrotic syndrome, proteinuria, renal impairment (five) and hematuria (one). Mean plasma creatinine concentration was 0.

Renal biopsy in children.

Between January 1973 and December 1986 a total of 47 children (32 boys) under the age of 16 years had a total of 60 renal biopsies. The commonest indication for biopsy was the nephrotic syndrome, followed by macroscopic haematuria, Henoch-Schönlein nephritis and lupus nephritis. The children have been followed prospectively for a mean period of five and one-half years.

Intravenous enoxacin for the treatment of acute pyelonephritis: pharmacokinetic and clinical study.

1. Eight women with acute pyelonephritis were treated with i.v.

Treatment of theophylline poisoning with haemoperfusion.

Two patients who had taken overdoses of theophylline were treated initially with oral activated charcoal. Owing to continued toxic plasma levels of theophylline, haemoperfusion was used to reduce rapidly theophylline levels. Both patients recovered rapidly.

Studies to assess the biological relevance of anti-Tamm-Horsfall protein antibodies detected by direct-binding enzyme-linked immunosorbent assay.

1. A role has been suggested for anti-Tamm-Horsfall protein (THP) antibodies in renal disease based on the results of immunoassays of pathological sera. The putative autoantibodies have not been isolated from such sera nor have definitive inhibition studies of their binding been carried out.

Loop-acting diuretics do not bind to Tamm-Horsfall urinary glycoprotein.

1. Binding between the radiolabelled loop-acting diuretics ([14C]frusemide, [14C]ethacrynic acid and [3H]bumetanide) and human Tamm-Horsfall glycoprotein or human serum albumin in vitro was evaluated by equilibrium dialysis. 2.