Clostridium difficile infection in Ohio hospitals and nursing homes during 2006.

Context: Healthcare data suggest that the incidence and severity of Clostridium difficile infection (CDI) in hospitals are increasing. However, the overall burden of disease and the mortality rate associated with CDI, including the contribution from cases of infection that occur in nursing homes, are poorly understood.

Objective: To describe the epidemiology, disease burden, and mortality rate of healthcare-onset CDI.