Background: Beriberi is endemic in South-east Asia. Diagnosis is based on clinical findings, but correlation of clinical features with blood thiamine concentrations is uncertain.
Objectives: To investigate in tachypnoeic Cambodian infants the correlation between whole blood thiamine diphosphate (TDP) concentrations, clinical findings and blood TDP levels after therapy.
Background: Beriberi is endemic in South-east Asia. Diagnosis is based on clinical findings, but correlation of clinical features with blood thiamine concentrations is uncertain. Objectives: To investigate in tachypnoeic Cambodian infants the correlation between whole blood thiamine diphosphate (TDP) concentrations, clinical findings and blood TDP levels after therapy.
View Article and Find Full Text PDFObjective: To determine the frequency of the prozone effect in patients with IgG4-related disease (IgG4-RD).
Methods: After identifying the prozone effect in an index patient with IgG4-RD, we examined additional samples to determine the frequency of this phenomenon. Thirty-eight serum samples obtained from patients with IgG4-RD whose results had been reported previously were retested.
Determination of urinary drug concentrations can prove to be very useful in the monitoring of patients who are receiving a variety of synthetic opioids. Through the use of liquid chromatography-tandem mass spectrometry, the simultaneous measurement of synthetic opioids provides for smaller sample volume requirements along with gains in throughput and an increase in the sensitivity of the analysis.
View Article and Find Full Text PDFBackground: World Health Organization advocates heat treatment of expressed breastmilk (EBM) as one method to reduce postnatal transmission of human immunodeficiency virus (HIV) in developing countries. Flash-heat is a simple heat treatment method shown to inactivate cell-free HIV.
Objective: To determine the effect of flash-heat on vitamin content of milk.