Patterns of DNA methylation as an indicator of biological aging: State of the science and future directions in precision health promotion.

Background: A rapidly expanding literature suggests that individuals of the same chronological age show significant variation in biological age.

Purpose: The purpose of this article is to review the literature surrounding epigenetic age as estimated by DNA methylation, involving the addition or removal of methyl groups to DNA that can alter gene expression without changing the DNA sequence.

Methods: This state of the science literature review summarizes current approaches in epigenetic age determination and applications of aging algorithms.

A discussion paper on stigmatizing features of diabetes.

Aim: This manuscript aims to describe stigmatizing features of diabetes.

Design: This article presents a narrative review of literature pertaining to stigma surrounding diabetes in different contexts.

Methods: A literature search was conducted in CINAHL, PubMed and Web of Science for qualitative studies published between 2007-2017.

The Complexities of "Struggling to Live Life".

Purpose The purpose of the study was to explore and describe perceptions and experiences of young adults with type 1 diabetes mellitus (T1DM) living in Appalachia, Tennessee. Methods Qualitative descriptive analysis of in-depth interviews of 9 young adults (male = 3, female = 6) 18 to 30 years of age living in Appalachian counties in Tennessee provided the basis of identifying the salient concerns from the perspective of this diverse group related to living daily with T1DM. Data analysis was facilitated by using NVivo 11 Pro and consisted of iterative review of the accounts in 3 phases: immersion, reduction, and interpretation.

Overweight in children: definitions, measurements, confounding factors, and health consequences.

The epidemic of childhood overweight continues to grow at staggering rates, increasing nearly four-fold between 1963 and 2000. Children that are overweight are more apt to be overweight adults and are more likely to suffer adverse health consequences associated with excess weight. Nurses have a unique presence in the healthcare environment to assess children for overweight, provide parent/child nutritional education, and conduct obesity-related research.