Reduced-intensity conditioning allogeneic transplantation after salvage treatment with DT-PACE in myeloma patients relapsing early after autologous transplant.

Objective: In this retrospective single-centre study, we have looked into the transplant outcomes(overall survival OS, progression-free survival PFS, GvHD) and the role of chimerism, DLI and pretransplant characteristics in patients who had a suboptimal response (<12 months) to an autologous stem cell transplant for myeloma and underwent an alemtuzumab T-cell depleted reduced-intensity allograft(RIC).

Methods: Twenty-four patients were salvaged with two cycles of DT-PACE and received a RIC transplant with fludarabine, melphalan and alemtuzumab. All the patients received PBSC grafts, eight patients had a sibling donor, and 16 had a graft from a fully matched unrelated donor.

Psychometric Properties and Construct Validity of the Knowledge Information Profile-Coumadin.

Oral anticoagulation therapy using Coumadin (warfarin) requires significant patient involvement. Limited validated instruments exist to test patient knowledge of Coumadin, and low health literacy may impede patient self-management. This article reports the psychometric testing of the Knowledge Information Profile-Coumadin (KIP-C20) to determine () minimum number of items and dimensions, () reliability, and () construct validity.

Survival of Campylobacter jejuni on beef and pork under vacuum packaged and retail storage conditions: examination of the role of natural meat microflora on C. jejuni survival.

The ability of Campylobacter jejuni ATCC 11168 to survive on beef and pork stored under chilled, vacuum packaged and retail display conditions were examined. In addition, the effect of natural microflora on commercial beef and pork on the survival of C. jejuni under these storage conditions was examined.

Exiting prostitution: an integrated model.

Exiting street-level prostitution is a complex, convoluted process. Few studies have described this process within any formal conceptual framework. This article reviews two general models and two prostitution-specific models and their applicability to the exiting process.

Using the teach-back and Orem's Self-care Deficit Nursing theory to increase childhood immunization communication among low-income mothers.

Guided by Orem's Self-care Deficit Nursing theory, the purpose of the pilot study was to assess the relationship between maternal health literacy and the mother's ability to comprehend and communicate information about childhood immunizations. Communication is the key to positive health results, particularly for patients with low literacy skills, yet few studies have examined patients' ability to converse about health information taught to them by providers. The study was conducted in an urban walk-in immunization clinic.

Mothers' knowledge and information needs relating to childhood immunizations.

The purpose of this pilot study was to determine mothers' literacy level and knowledge, information needs, and information-seeking behaviors related to the vaccine(s) their children were receiving. A convenience sample of 15 mothers with one child and 15 mothers with two or more children was recruited at a free, urban, walk-in immunization clinic in Detroit. Participants completed the REALM test and a demographic form.

Health sciences librarians' attitudes toward the Academy of Health Information Professionals.

Objectives: The purpose of the study was to ascertain health sciences librarians' attitudes toward the Academy of Health Information Professionals (AHIP).

Sample: Systematic sampling was used to select 210 names from the list of members of the Midwest Chapter of the Medical Library Association.

Methods: A questionnaire containing open- and closed-ended questions was used to collect the data.

An exploratory study of the health problems, stigmatization, life satisfaction, and literacy skills of urban, street-level sex workers.

An exploratory study of 26 female urban, street-level sex workers was conducted to gather information about their health problems, feelings of stigmatizations, satisfaction with life, and literacy skills. Each woman completed the health questionnaire, Stigmatization Scale, Satisfaction with Life Scale, and the Rapid Estimate of Adult Literacy in Medicine. Twenty-one women had acute or chronic health problems; only eleven sought health care.

Information needs at the end of life: a content analysis of one person's story.

During the last phase of life, a person may need a variety of information to help her or him cope with dying and death. This article describes the nature of information needed during this stage. A content analysis was done of a book of conversations between a husband who was dying and his wife who is a grief counselor to determine his information needs.

Bacterial contamination of recirculating brine used in the commercial production of moisture-enhanced pork.

In a commercial process for the production of moisture-enhanced pork, boneless pork loins were conveyed through a recirculating injection apparatus, and brine (sodium phosphate, sodium chloride, and lemon juice solids) was pumped into the meat through banks of needles inserted automatically into the upper surfaces of cuts. Brine samples were collected at intervals during the production process and analyzed to determine the total plate count and the numbers of lactic acid bacteria, pseudomonads, Brochothrix thermosphacta, and Enterobacteriaceae. Listeria monocytogenes numbers in the brine were determined using a PCR with primers for the hemolysin gene in combination with a most probable numbers determination.

Effects of treatment with lysozyme and nisin on the microflora and sensory properties of commercial pork.

A mixture of lysozyme and nisin at a ratio of 3:1 (w/w) and at a surface concentration of approximately 260 microg/cm2 was effective in controlling the growth of lactic acid bacteria, lactic acid bacteria able to grow in the presence of acetate and Brochothrix thermosphacta on naturally contaminated pork loins that were stored in vacuum packages at 2 degrees C for up to 6 weeks. When loins were removed, cut into chops, and displayed in a retail display case, the efficacy of the antimicrobial mixture decreased with increasing display time. At most sampling times, bacterial numbers were lower in treated samples than in untreated samples.

Developing end-of-life interdisciplinary programs in universitywide settings.

Interdisciplinary programs in end of life are widely discussed as valuable, particularly approaches to end-of-life care. Despite this emphasis, interdisciplinary programs have not been easy to implement. In universities, the implementation of interdisciplinary programs encounters administrative obstacles, including credit for the time spent in these group efforts and "ownership" of interdisciplinary courses (IDCs).

General health problems of inner-city sex workers: a pilot study.

Objective: A pilot study was designed to determine the general health problems of inner city sex workers.

Sample: The researchers worked with an agency that provides outreach services to these sex workers. Through this agency, they had access to a purposive sample of sex workers in a large Midwest city.