Publications by authors named "Lydie Porte"
Article Synopsis
- The study looked at how infective endocarditis (IE) affects pregnant women who don’t use drugs and included cases from 14 hospitals over many years.
- Most women in the study were around 33 years old and had their babies about 30 weeks along; many had no prior heart issues.
- Most women faced serious problems, like heart failure and complications with their pregnancies, including some that resulted in surgery or even loss of the baby; one woman sadly died from the illness.
Background: Preventive strategies for invasive aspergillosis (IA) have still not been determined in heart transplant recipients whereas IA leads to a high mortality rate at 12 months posttransplantation. The use of voriconazole or echinocandins was proposed but can favor emergence of Aspergillus or Candida sp. resistant strains or promote neurological and liver disorders in some patients.
View Article and Find Full Text PDFBackground: The prognostic impact of residual vegetation (RV) after medical treatment for endocarditis remains unknown.
Methods: 134 consecutive patients hospitalized for infective endocarditis, not surgically treated, with the presence of vegetation at diagnosis, were included retrospectively. The follow-up started at the end of antibiotic treatment when healing was complete.
Article Synopsis
- The study aimed to analyze the clinical features and outcomes of invasive mold infections (IMI) in patients who received solid organ transplants (SOT) between 2008 and 2016.
- Out of 1,739 transplant recipients, 68 developed IMI, primarily invasive aspergillosis (IA), with a yearly incidence varying based on the organ transplanted, being highest in heart transplants.
- Key findings indicated that the need for vasoactive drugs and positive direct examinations were significant predictors of one-year mortality in patients with IA, highlighting the importance of initial care and fungal load in treatment outcomes.
Quinine monitoring should be based on unbound concentration due to variable unbound fraction in malaria patients.
View Article and Find Full Text PDFBackground: Progressive multifocal leukoencephalopathy (PML), a rare devastating demyelinating disease caused by the polyomavirus JC (JCV), occurs in severely immunocompromised patients, most of whom have advanced-stage HIV infection. Despite combination antiretroviral therapy (cART), 50% of patients die within 6 months of PML onset. We conducted a multicenter, open-label pilot trial evaluating the survival benefit of a five-drug cART designed to accelerate HIV replication decay and JCV-specific immune recovery.
View Article and Find Full Text PDFInconsistent results have been reported for the semen quality in HIV-infected men, due to the biases inherent in some studies. The objective of the present study was to investigate the semen parameters in HIV-1-infected patients and to compare their sperm characteristics with those of a control group of fertile, noninfected men. Factors implicated in semen alterations in HIV-1 patients were also analyzed.
View Article and Find Full Text PDFWe describe 2 patients with spinal cord compression that occurred in the course of biopsy-proven giant cell arteritis (GCA). One case was due to an epidural tumorlike inflammatory lesion, the other to a concentric inflammatory thickening of the meninges. Both patients were highly corticodependent; they had low-titer anti-neutrophil cytoplasmic antibodies but no antimyeloperoxidase or antiproteinase 3 autoantibodies.
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