Mode action prediction of catechin from Roxb. against UDP--acetylenolpyruvyl-glucosamine reductase (MurB enzyme) of : study.

The prevalence of oral health problems in the global population is still high, especially dental caries, which is considered a multifactorial disease involving the role of bacteria, namely . Gram-positive bacteria metabolize carbohydrates and sugars and convert them into lactic acid, causing dental caries. The peptidoglycan (PG) layer at the outer surface of the bacteria acts as protection.