Publications by authors named "Lydia Yu"
Doxorubicin (DOX) is one of the most effective chemotherapeutics for canine high-grade lymphoma. In addition to dose-dependent chronic cardiotoxicity, DOX can trigger acute cardiac arrhythmias during drug infusion. Diphenhydramine premedication is commonly used, as histamine release is a proposed mechanism for DOX-associated arrhythmogenesis.
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- Arterial inflammation from atherosclerosis is a leading global cause of death, with HDAC9 identified as a key player in the disease's progression and complications like stroke and heart attacks.* -
- Research using hyperlipidemic mice shows that inhibiting HDAC9 with a small molecule (TMP195) reduces inflammation and stabilizes atherosclerotic plaques by affecting macrophage and endothelial cell behavior.* -
- TMP195 not only mitigates lesions and their vulnerability but also lowers inflammatory markers in monocytes from patients with atherosclerosis, indicating its potential as a therapeutic approach for atheroprotection.*
The present shortage of nurses in the United States is expected to continue. Nurse shortage, the nature of the work environment, and employers' expectations and attitudes, among other factors, influence both nurse retention and quality of patient care. The Nurse-Friendly Hospital Project was designed to improve nurses' work environment in rural and small hospitals in Texas.
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