Malignant ovarian germ cell tumors: identification of novel prognostic markers and long-term outcome after multimodality treatment.

Purpose: Malignant ovarian germ cell tumors are rare and knowledge about prognostic parameters currently is limited. This study was undertaken to evaluate long-term outcome of patients with malignant ovarian germ cell tumors (MOGCTs) after chemotherapy and to assess prognostic parameters.

Patients And Methods: A total of 113 patients with stage IC to IV MOGCTs were included into this retrospective study.

Management of brain metastases in patients with high-risk gestational trophoblastic tumors.

Objective: To analyze the results of current treatment of patients with brain metastases from high-risk gestational trophoblastic tumors.

Study Design: Consecutive patients treated between June 1981 and the end of 2000 with brain metastases from high-risk gestational trophoblastic tumors were selected from our computerized database.

Results: There were 39 patients with cerebral metastases from high-risk gestational trophoblastic tumors, and 30 (79.