Publications by authors named "Lydia Cox"
A Ti(Oi-Pr) promoted 5- or 6-endo-trig cyclisation to make nitrogen heterocycles is presented. The utilisation of HFIP as a key solvent enables the stereoselective preparation of di- & tri-substituted pyrrolidines and piperidines while forming a new C-C bond at the same time. The process is triggered by a cationic intermediate generated from an allylic or benzylic alcohol and leads to the simultaneous generation of both a C-C and a C-N bond in a single step.
View Article and Find Full Text PDFRh-catalyzed carbonylative C-C bond activation of cyclopropylamides generates configurationally stable rhodacyclopentanones that engage tethered alkenes in (3+1+2) cycloadditions. These studies provide the first examples of multicomponent cycloadditions that proceed through C-C bond activation of "simple" electron poor cyclopropanes.
View Article and Find Full Text PDFArticle Synopsis
- The study aims to explore how families adapt and support siblings of children undergoing hematopoietic stem cell transplant (HSCT).
- Through interviews with families and healthcare providers, several sibling-related challenges were identified, such as feelings of exclusion, emotional difficulties, and added responsibilities.
- Families reported various strategies to help siblings cope, including sharing information, leveraging social support, and providing special experiences or roles during the transplant process.