Treatment of proteinuria in dogs with telmisartan: A retrospective study.

Background: Use of telmisartan for the treatment of proteinuria in dogs has not been thoroughly investigated.

Hypothesis/objectives: Telmisartan can be effective for the treatment of proteinuria in dogs.

Animals: Forty-four client-owned dogs with proteinuria.

Use of surgery and mitoxantrone chemotherapy in a dog with disseminated lymphangiosarcoma.

Case Description: A 5-year-old sexually intact male Giant Schnauzer was evaluated because of difficulty breathing and left pelvic limb swelling. Eighteen months previously, the patient had had intermittent left pelvic limb swelling, but the owner declined further testing at that time.

Clinical Findings: Physical examination revealed severe pitting edema of the left pelvic limb and prepuce and muffled heart sounds on thoracic auscultation.

Use of recombinant human thyroid-stimulating hormone for thyrotropin stimulation test in healthy, hypothyroid and euthyroid sick dogs.

Recombinant human thyroid-stimulating hormone (rhTSH) was evaluated for the diagnosis of canine hypothyroidism, using TSH response tests. Phase I stimulation tests were performed in 6 healthy dogs weighing over 20 kg, using 50 and then 100 microg of freshly reconstituted rhTSH administered intravenously. In phase II, the same dogs were stimulated by using 100 microg of rhTSH frozen for 3 months at -20 degrees C.