Publications by authors named "Lv Qian-Qian"
Background: Existing evidence has shown that metabolic disturbances may be involved in the pathological process of autism spectrum disorder(ASD). This study aimed to investigate the alterations of serum amino acid concentration profiles in Chinese Han children with ASD.
Methods: Serum amino acid levels were measured using tandem mass spectrometry in 60 children with ASD and 30 typically developing (TD) controls.
Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders that shown a close association with impaired lipid metabolism. The acyl-carnitine spectrum status in Chinese children with ASD has not been reported. In this study, we assessed the levels of blood acyl-carnitines in Chinese children with ASD and examined the relation between acyl-carnitine profiles and the intelligence levels.
View Article and Find Full Text PDFMetabolic profiling of dehydrodiisoeugenol using xenobiotic metabolomics.
J Pharm Biomed Anal
October 2017
Article Synopsis
- * Thirteen DDIE metabolites were identified, including seven reported for the first time, using advanced mass spectrometry techniques, revealing important metabolic pathways like demethylation and ring-opening.
- * The enzyme CYP1A1 was found to play a significant role in metabolite formation, and exposure to DDIE increased levels of specific endogenous metabolites in mouse urine, suggesting its influence on gut microbiota.