Publications by authors named "Luzia Bruns"
Objective: Systemic sclerosis (SSc) is a severe rheumatic disease causing fibrotic tissue rearrangement. Aberrant toll-like receptor (TLR) 8 transcripts in plasmacytoid dendritic cells (pDCs) were recently linked to SSc pathogenesis, which is at least partially mediated by increased type I interferon (IFN-I) responses. Here, we addressed the functional role of TLR8 signaling in different immune cell subsets of patients with SSc.
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- * Of the 219 patients studied, 12.3% were diagnosed with cancer, with gastric cancer, non-melanoma skin cancer, and non-Hodgkin lymphoma being the most common types. Certain immune-related health issues were found to be linked to cancer diagnoses.
- * Genetic testing identified potential inherited cancer risks in about 14.3% of these patients, suggesting that some CVID patients may have a genetic predisposition to certain cancers.
Background And Objective: The work situation is an important dimension of professional life and wellbeing, and a policy lever to strengthen recruitment and retention. This study aims to explore the work situation of physicians and residents in internal medical rheumatology, considering the impact of the coronavirus pandemic COVID-19.
Methods: A questionnaire-based online survey was conducted in early 2021 at the Hannover Medical School, supported by the German Society of Rheumatology.
Background And Objective: Health workforce shortage in German rheumatology has been identified as a healthcare service and delivery problem. Health policy has increased staffing targets, yet effective intervention strategies are lacking. This research aimed to systematically map the rheumatology workforce to improve the evidence for interventions and explore possibilities for more effective health workforce management.
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