Symptomatic bilateral xanthogranulomas of choroid plexus in a child.

Choroid plexus xanthogranulomas are uncommon lesions that occur almost exclusively in adults; most of them constitute incidental autopsy findings. A case of symptomatic bilateral xanthogranulomas of choroid plexus in a 6 year-old girl with progressive visual loss is reported. Theories on the pathogenesis of this entity are reviewed.

Cavitated (cystic) falcine chondroma: case report.

Intracranial chondromas are unusual tumours that commonly arise from the bones of the skull base. Extraosseous instances are extremely rare. The authors report the case of a 14-year-old boy with a cavitated (cystic) falcine chondroma originating in the falx cerebri.

[Sudanophilic cavitating leukodystrophy: adult familial form].

Sudanophilic cavitating leukodystrophy is an unusual disorder of the cerebral white matter, clinically characterized by deafness, mental retardation, behavioural alterations and lesions of the descending long tracts. Neuropathological features include: extensive subcortical and deep central demyelination, conspicuous astrocytosis and macro and micro cavitation. We describe a 34 year-old male with personal and family history, clinical features and neuropathological changes consistent with Sudanophilic cavitating leukodystrophy.

[Creutzfeldt-Jakob disease. Report of 2 cases].

The authors report two cases of Creutzfeldt Jakob disease in a 48 year old woman and a 60 year old man. This demential disorder is induced by a non conventional virus and its characterized from a clinical point of view by progressive dementia, myoclonus and seizures, it follows a subacute course with progressive deteriorization that invariably leads to death. Neuropathological features include: neuronal loss, astrocytosis and neuropil vacuolization in cortical areas of the brain.