Diabetic Striatopathy: An Extremely Rare Form of Diabetes Mellitus End-Organ Lesions.

Diabetes mellitus is one of the most frequent endocrinopathies in the medical routine, appearing across different specialties. Although neurological involvement in the form of peripheral neuropathy is the most recurrent form acknowledged by physicians, the spectrum of neurological involvement can be more diverse. Here, we present a case of diabetic striatopathy, a rare neurological manifestation of diabetes mellitus with poor metabolic control, in a patient whose epidemiological group was not classically.

Galectin-3 plays a key role in controlling infection by in human trophoblast cells and human villous explants.

Galectin-3 (Gal-3) is a β-galactoside-binding lectin expressed in cells of the placental microenvironment. This lectin is involved in various biological processes, such as modulation of the immune system and control of parasitic illness. infection can lead to congenital transmission and cause miscarriages, prematurity and fetal anomalies.

Can you Diagnose Immune Thrombocytopenia in Myeloma? A Case of Thrombocytopenia in a Patient with Multiple Myeloma.

Unlabelled: Multiple myeloma (MM) is the second most common haematological malignancy, the diagnosis of which has doubled in recent years. Immune thrombocytopenia consists of isolated thrombocytopenia secondary to antibody mediated peripheral platelet destruction. In most cases, there is no identifiable cause (primary immune thrombocytopenia).

Combining ability for agronomic traits among commercial maize hybrids under low and high nitrogen inputs targeting the development of breeding populations.

Commercial hybrids are the main germplasm source for developing maize lines in breeding programs in Brazil; additionally, nitrogen (N) is one the major limiting maize production in Brazilian tropical areas. Here, we assessed the combining ability among ten commercial hybrids under contrasting N inputs and selected the best parental hybrids to develop breeding populations for optimal and N-stress environments. We evaluated the 45 F1 crosses for agronomic traits under contrasting N inputs and over two summer seasons.

Associations between Biological Maturation, Chronological Age, Body Mass Index, Sex, and Motor Competence in Prepubertal Children: A Network Analysis.

Background: The development of motor competence (MC) during childhood is crucial for future physical activity and health outcomes, and it is affected by both biological and psychosocial factors. Most MC research has focused on children's age, with fewer studies examining separate associations between MC and biological maturation.

Methods: This cross-sectional study used network analysis to assess the nonlinear associations between biological maturation (the child's percentage of predicted mature stature to indicate somatic maturation), chronological age, sex, BMI, and MC (Test of Gross Motor Development, third edition) in 218 children (100 boys, 118 girls) aged 7-9 years.

Epidemic curves and the profile of patients hospitalized by COVID-19 in a border region.

Objective: to describe the epidemic curves and analyze the epidemiological profile of patients hospitalized with COVID-19 in a triple border city.

Method: descriptive-quantitative. The population consisted of COVID-19 cases that required hospitalization, analyzing variables such as: age, gender, race/color, city where they lived, occupation, pregnant woman, institutionalized patient and evolution.

Copaifera spp. oleoresins control Trypanosoma cruzi infection in human trophoblast cells (BeWo) and placental explants.

Congenital Chagas disease (CCD) is a worldwide neglected problem with significant treatment limitations. This study aimed to evaluate the potential of Copaifera spp. oleoresins (ORs) against Trypanosoma cruzi infection in trophoblast cells (BeWo lineage) and human chorionic villous explants (HCVE).

STudy to ActivelY WARM trauma patients (STAY WARM): a pilot study assessing feasibility of self-warming blankets in patients requiring a massive hemorrhage protocol activation.

Purpose: Massively bleeding trauma patients often arrive to intensive care units hypothermic. Active warming blankets have shown promise in reducing hypothermia in the pre-hospital setting, but less is known about their in-hospital use. The aim of this pilot evaluation was to understand the feasibility of the Ready-Heat blanket in a level 1 trauma centre to improve the management of hypothermia in massively bleeding trauma patients.

Revealing the ESIPT process in benzoxazole fluorophores within polymeric matrices through theory and experiment.

The impact of the polymeric matrix on the photophysical characteristics of monomeric dyes responsive to excited-state intramolecular proton transfer (ESIPT) was investigated through UV-Vis absorption as well as steady-state and time-resolved emission spectroscopies. For this purpose, two benzoxazole monomers (M1 and M2) with acryloyl groups at different positions in their molecular structures were employed to facilitate covalent bonding within a styrene chain. Our findings reveal significant variations in their excited-state properties due to the proximity of the acryloyl groups, which affects the energy barrier of the ESIPT reaction, the emission wavelength, and the balance between the normal and tautomeric forms.

Biological maturation, fat mass and cardiorespiratory fitness in prepubescent girls: A mediation analysis.

Background: The association between indicators of maturation and measures of physical fitness are not well correlated and vary according to chronological age, sex, body size, and motor characteristics. It is known that chronological age, maturation, and fat mass are significant predictors of cardiorespiratory fitness in girls, however, the contributions of fat mass to the relationship between maturation and endurance performance are still unclear.

Objective: The current study aimed to examine whether the association between somatic maturation and running performance in the 20-m shuttle-run in girls is mediated by estimated fat mass.

Impact on pulmonary, cardiac, and renal function and long-term quality of life after hospitalization for acute respiratory distress syndrome due to COVID-19: Protocol of the Post-COVID Brazil 3 study.

Rationale: Evidence about long-term sequelae after hospitalization for acute respiratory distress syndrome due to COVID-19 is still scarce.

Purpose: To evaluate changes in pulmonary, cardiac, and renal function and in quality of life after hospitalization for acute respiratory distress syndrome secondary to COVID-19.

Methods: This will be a multicenter case-control study of 220 participants.

Development of a Microwave-Assisted Bench Reactor for Biomass Pyrolysis Using Hybrid Heating.

Microwave-assisted pyrolysis (MAP) is a cutting-edge technology that converts biomass into fuels, chemicals, and materials. In this study, an Arduino was used to control and automate a MAP system built from a microwave oven with a cordierite chamber filled with silicon carbide. Sugar cane bagasse was pyrolyzed at 250, 350, 450, and 550 °C to validate the MAP system and obtain pyrolytic products with different yields and chemical compositions.

Dried Plasma for Major Trauma: Past, Present, and Future.

Uncontrollable bleeding is recognized as the leading cause of preventable death among trauma patients. Early transfusion of blood products, especially plasma replacing crystalloid and colloid solutions, has been shown to increase survival of severely injured patients. However, the requirements for cold storage and thawing processes prior to transfusion present significant logistical challenges in prehospital and remote areas, resulting in a considerable delay in receiving thawed or liquid plasma, even in hospitals.

Case Report: Transcatheter aortic valve implantation using balloon-expandable bioprosthesis in patients with severe pure aortic regurgitation on noncalcified native valves: a series of cases.

Background: For individuals with pure aortic regurgitation (AR), transcatheter aortic valve implantation (TAVI) is cautiously recommended only for those with a high or prohibitive surgical risk. We aimed to describe the results of a case series of transcatheter implantation of a balloon-expandable aortic valve bioprosthesis (BEV) for the treatment of noncalcified native valve AR.

Methods: From February 2022-November 2022, we performed TAVI in patients with severe pure AR.

Update on chelating agents in endodontic treatment: A systematic review.

Background: The aim of this review was to assess the evidence regarding the most commonly used chelating agents in terms of efficacy, erosive potential, cytotoxicity, interaction, antimicrobial effect, impact on sealers adhesion, and release of growth factors.

Material And Methods: MEDLINE (PubMed) database, Cochrane Library and Scopus were searched up to January 14, 2023, including studies with one or more of the following chelating agents: 17% EDTA, 9% and 18% HEDP, 10% and 20% citric acid, 2%-2.25% peracetic acid and 7% maleic acid.

Knowledge, attitudes and practices of cervical cancer screening among female students enrolled in higher education institutions in Cabo Verde.

Unlabelled: Cervical cancer (CC) is the fourth most common cancer among women in the world and the second in Africa. CC is the third most frequent cancer and the first cause of cancer-related death among women in Cabo Verde, with an estimated incidence of 17 cases per 100,000 women. The mortality rate is around 10.

Fentogram electrochemical detection of HIV RNA based on graphene quantum dots and gold nanoparticles.

This work reports the construction of an HIV-specific genosensor through the modification of carbon screen-printed electrodes (CSPE) with graphene quantum dots decorated with L-cysteine and gold nanoparticles (cys-GQDs/AuNps). Cys-GQDs were characterized by FT-IR and UV-vis spectra and electronic properties of the modified electrodes were evaluated by cyclic voltammetry and electrochemical impedance spectroscopy. The modification of the electrode surface with cys-GQDs and AuNps increased the electrochemical performance of the electrode, improving the electron transfer of the anionic redox probe [Fe(CN)] on the electrochemical platform.

Post-Reconstitution Hemostatic Stability Profiles of Canadian and German Freeze-Dried Plasma.

Despite the importance of the hemostatic properties of reconstituted freeze-dried plasma (FDP) for trauma resuscitation, few studies have been conducted to determine its post-reconstitution hemostatic stability. This study aimed to assess the short- (≤24 h) and long-term (≥168 h) hemostatic stabilities of Canadian and German freeze-dried plasma (CFDP and LyoPlas) after reconstitution and storage under different conditions. Post-reconstitution hemostatic profiles were determined using rotational thromboelastometry (ROTEM) and a Stago analyzer, as both are widely used as standard methods for assessing the quality of plasma.

Electrochemical Diselenation of BODIPY Fluorophores for Bioimaging Applications and Sensitization of O.

Invited for the cover of this issue are the groups of Holger Braunschweig at the Julius-Maximilians-Universität Würzburg, Germany and Eufrânio N. da Silva Júnior at the Universidade Federal de Minas Gerais, UFMG, Brazil. The image depicts the electrochemical synthesis of selenium-containing BODIPY molecules with lightning symbolizing the electrifying synthetic process, while the surrounding elemental chaos hints at the red-shifted absorption and emission and the transformative photophysical properties of these new compounds.

Unveiling a Strategy for Ring Opening of Epoxides: Synthesis of 2-Hydroxyindolinylidenes Using α-Ester Sulfoxonium Ylides.

The untapped potential of α-carbonyl sulfoxonium ylides in epoxide ring-opening reactions has been a notable gap in current research, with such reactivity predominantly associated with the highly reactive dimethylsulfoxonium methylide. This study introduces an innovative approach wherein an epoxide indole, formed from 2-hydroxyindoline-3-triethylammonium bromide, undergoes reaction with α-ester sulfoxonium ylides. The outcome is the efficient synthesis of a range of 2-hydroxyindolin-3-ylidenes, demonstrating favorable yields (41-81%) and / ratios from 4:1 to those of exclusive isomers.

Electrochemical Diselenation of BODIPY Fluorophores for Bioimaging Applications and Sensitization of O.

We report a rapid, efficient, and scope-extensive approach for the late-stage electrochemical diselenation of BODIPYs. Photophysical analyses reveal red-shifted absorption - corroborated by TD-DFT and DLPNO-STEOM-CCSD computations - and color-tunable emission with large Stokes shifts in the selenium-containing derivatives compared to their precursors. In addition, due to the presence of the heavy Se atoms, competitive ISC generates triplet states which sensitize O and display phosphorescence in PMMA films at RT and in a frozen glass matrix at 77 K.