Publications by authors named "Luyi Lv"
Purpose: The objective of this study is to assess the carrier frequency and pathogenic variation of monogenetic diseases in a population of 114 subjects in Han Chinese from Hebei province who are undergoing assisted reproductive technology through the utilization of Expanded Carrier Screening (ECS).
Methods: The study utilized a panel consisting of 155 severe monogenic recessive genetic diseases for ECS. Next-generation sequencing technology was employed to identify specific variants associated with ECS in a cohort of 114 subjects from 97 couples, comprising 97 females and 17 male spouses.
Molecular regulation of DNA damage and repair in female infertility: a systematic review.
Reprod Biol Endocrinol
August 2024
Article Synopsis
- DNA damage can hurt the development of eggs and embryos, which are important for getting pregnant and having healthy babies.
- Things like getting older, certain medicines like chemotherapy, and other factors can make DNA in a woman’s eggs weaker, leading to difficulties in having kids.
- Scientists are studying how to fix or prevent DNA damage in eggs to help with infertility problems, focusing on diseases that affect fertility like PCOS and endometriosis.
Background: Cryptococcal meningitis (CM) is an inflammatory mycosis of the central nervous system caused by meninge infection or brain parenchyma with Cryptococcus species. It is associated with high morbidity and mortality, and patients with acquired immune deficiency syndrome are particularly susceptible. There have been increasing reports of CM in HIV-negative patients in China over the last few years.
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