Composite-Observer-Based Adaptive Consensus Tracking Control for Nonlinear MASs With Unknown Control Directions Against Deception Attacks.

This article primarily studies the adaptive output-feedback consensus tracking control issue for nonlinear multiagent systems (MASs) with unknown control directions against deception attacks. First, a composite observer combining the state observer and the disturbance observer is developed to concurrently estimate the states of confronting deception attacks and unmeasurable disturbances. Moreover, to resolve the unknown gains resulting from deception attacks, the adaptive attack compensator is proposed.

Metabolite-derived damage-associated molecular patterns in immunological diseases.

Damage-associated molecular patterns (DAMPs) are typically derived from the endogenous elements of necrosis cells and can trigger inflammatory responses by activating DAMPs-sensing receptors on immune cells. Failure to clear DAMPs may lead to persistent inflammation, thereby contributing to the pathogenesis of immunological diseases. This review focuses on a newly recognized class of DAMPs derived from lipid, glucose, nucleotide, and amino acid metabolic pathways, which are then termed as metabolite-derived DAMPs.

DEHP exposure elevated cardiovascular risk in obese mice by disturbing the arachidonic acid metabolism of gut microbiota.

Phthalate esters (PAEs) are one of the significant classes of emerging contaminants that are increasingly detected in environmental and human samples. Nevertheless, the current toxicity studies rarely report how PAEs affect the cardiovascular system, especially in obese individuals. In this study, diet-induced obese mice and corresponding normal mice were exposed to di(2-ethylhexyl) phthalate (DEHP) by oral gavage at environmentally relevant concentrations and key characteristics of cardiovascular risk were examined.

Toll-like receptors 7 and 9 regulate the proliferation and differentiation of B cells in systemic lupus erythematosus.

Systemic lupus erythematosus (SLE) is an autoimmune illness marked by the loss of immune tolerance and the production of autoantibodies against nucleic acids and other nuclear antigens (Ags). B lymphocytes are important in the immunopathogenesis of SLE. Multiple receptors control abnormal B-cell activation in SLE patients, including intrinsic Toll-like receptors (TLRs), B-cell receptors (BCRs), and cytokine receptors.

The protective effects of taurine and fish oil supplementation on PM-induced heart dysfunction among aged mice: A random double-blind study.

As it is nearly impossible to reduce PM concentrations in most cities to safe limits in a short period of time, dietary supplementation presents a promising approach for mitigating the adverse effects of PM exposure. A cross-sectional study showed that the elderly population of Linfen (PM: 102 μg/m) exhibited significantly lower serum taurine levels, as well as higher oxidative stress levels and cardiovascular health risks, than the corresponding population in Guangzhou (PM: 39 μg/m). We conducted a random double-blind study on aged mice that employed a "real-world" PM exposure system to simulate the conditions of Linfen with the aim of investigating the protective effects of taurine and fish oil supplementation on PM-induced heart dysfunction.