Publications by authors named "Luwen Ren"
Background: The cesarean delivery (CD) rate has been increasing globally. Trial of labor after cesarean delivery (TOLAC) has been used as a key method for the reduction of the CD rate. Little is known, however, about the association between the second-stage duration of TOLAC and adverse maternal and neonatal outcomes.
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- - Maternal sepsis is a significant issue causing health problems for pregnant women and newborns, with a specific focus on its occurrence in China.
- - A study analyzed data from over 70,000 obstetric patients to understand the causes and risk factors for maternal sepsis, finding that 12.3% of infections were linked to sepsis and identifying several key risk factors.
- - Major risk factors for maternal sepsis included emergency hospital admissions, lack of prenatal care, labor induction, cervical cerclage, and being in the first or second trimester of pregnancy, with the uterus commonly being the infection site.
Objectives: Successful pregnancy involves the homeostasis between maternal decidua and fetoplacental units, whose disruption contributes to compromised pregnancy outcomes, including recurrent spontaneous abortion (RSA). The role of cell heterogeneity of maternal decidua in RSA is yet to be illustrated.
Materials And Methods: A total of 66,078 single cells from decidua samples isolated from patients with RSA and healthy controls were analysed by unbiased single-cell RNA sequencing (scRNA-seq).
To determine the factors predicting the probability of severe postpartum hemorrhage (SPPH) in women undergoing repeat cesarean delivery (RCD). This multicenter, retrospective cohort study involved women who underwent RCD from January 2017 to December 2017, in 11 public tertiary hospitals within 7 provinces of China. The all-variables model and the multivariable logistic regression model (pre-operative, operative and simple model) were developed to estimate the probability of SPPH in development data and external validated in validation data.
View Article and Find Full Text PDFPurpose: Through this study, we aimed to evaluate the effects of different types of placenta previa (PP) on maternal and neonatal outcomes.
Methods: This study was conducted in The Third Affiliated Hospital of Guangzhou Medical University and Tongji Hospital between January 2009 and 2019. PP was traditionally classified into four types, namely low-lying placenta, marginal, partial, and complete PP.
Effect of previous placenta previa on outcome of next pregnancy: a 10-year retrospective cohort study.
BMC Pregnancy Childbirth
April 2020
Background: To determine the effects of previous placenta previa on the maternal and neonatal outcomes of the next pregnancy.
Methods: This 10-year retrospective cohort study was conducted in the Department of Obstetrics and Gynecology, Third Affiliated Hospital of Guangzhou Medical University, between January 2009 and 2018. We retrospectively analyzed the effects of a previous singleton pregnancy in women with and without placenta previa on the outcomes of the subsequent pregnancy.
The aim of this study was to identify risk factors among obstetric patients admitted to the intensive care unit (ICU).The study was conducted in Third Affiliated Hospital of Guangzhou Medical University during January 1, 2009 and December 31, 2016. A total of 44,817 pregnant women ≥20 weeks of gestational age were scanned.
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