Environ Sci Pollut Res Int
August 2023
Improving carbon emission efficiency is crucial for realizing carbon neutralization. Many critical influencing factors of carbon emission efficiency were identified by previous studies, but they ignored the impact of carbon capture, utilization, and storage (CCUS) technology, which is considered in this study. By employing the panel fixed effect, the moderating effect, and the panel threshold regression models, this study investigates the influence of CCUS technology on carbon emission efficiency and how that impact fluctuates when digital economy is incorporated.
View Article and Find Full Text PDFThis work aims to evaluate the changes in cerebrospinal fluid (CSF) hydrodynamics in patients diagnosed with communicating hydrocephalus. Besides, we establish the relationship between CSF flow dynamic parameters on the midbrain aqueduct and intracranial pressure (ICP). CSF hydrodynamics analysis was performed using Phase-Contrast Magnetic Resonance Imaging (PC-MRI) techniques on the midbrain aqueduct of 41 patients diagnosed with communicating hydrocephalus and 22 healthy volunteers.
View Article and Find Full Text PDFBackground And Purpose: Epilepsy is one of the most common diseases of the nervous system. Approximately one-third of epilepsy cases are drug-resistant, among which generalized-onset seizures are very common. The present study aimed to analyze abnormalities of the thalamocortical fiber pathways in each hemisphere of the brains of patients with drug-resistant generalized epilepsy.
View Article and Find Full Text PDFPurpose: Epilepsy is considered a disorder of neural networks. Patients diagnosed with refractory epilepsy frequently experience attention impairments. Seizure activity in epilepsy may disturb brain networks and damage the brain function of attention.
View Article and Find Full Text PDFCurr Cancer Drug Targets
May 2016
Aberrant expression of the MDR1-encoded P-glycoprotein (P-gp) is often associated with clinical multi-drug resistance (MDR) leading to poor prognosis and failure of chemotherapy. However, the precise and cooperative molecular mechanism responsible for MDR1 transcription and expression in acquired MDR remains elusive. We, herein, demonstrate that Wnt/β-catenin signal pathway is constitutively activated in Doxorubicin-induced MDR cancer cells, in which nuclear β -catenin specifically interacts with the transcriptional coactivator CBP in a MEK(1/2)/ERK(1/2) signal-dependent manner.
View Article and Find Full Text PDF