A Novel Chest-Based PPG Measurement System.

Advancements in integrated circuit (IC) technology have accelerated the miniaturization of body-worn sensors and systems, enabling long-term health monitoring. Wearable electrocardiogram (ECG), finger photoplethysmogram (PPG), and wrist-worn PPG have shown great success and significantly improved life quality. Chest-based PPG has the potential to extract multiple vital signs but requires ultra-high dynamic range (DR) IC to read out the small PPG signal among large respiration and artifacts inherent in daily life.

Physiological Profiling of Agitation in Dementia: Insights From Wearable Sensor Data.

Background And Objectives: The number of people with dementia is expected to triple to 152 million in 2050, with 90% having accompanying behavioral and psychological symptoms (BPSD). Agitation is among the most critical BPSD and can lead to decreased quality of life for people with dementia and their caregivers. This study aims to explore objective quantification of agitation in people with dementia by analyzing the relationships between physiological and movement data from wearables and observational measures of agitation.

Simulation of ambulatory electrodermal activity and the handling of low-quality segments.

Background And Objectives: Monitoring electrodermal activity (EDA) in daily life requires effective handling of low-quality segments, which are common in ambulatory EDA data. Although several low-quality handling methods have been implemented, systematic comparison of these methods, which requires a large annotated dataset, is lacking.

Methods: Therefore, we proposed the simulation of realistic ambulatory EDA data starting from high-quality EDA signals, which were subsequently contaminated with varying concentrations of artifacts.

Mild daily stress, in interaction with NR3C1 DNA methylation levels, is linked to alterations in the HPA axis and ANS response to acute stress in early adolescents.

Background: Daily Hassles (DH) or daily stress - is a mild type of stressor with unique contributions to psychological distress. Yet, most prior studies that investigate the effects of stressful life experiences focus on childhood trauma or on early life stress and little is known about the effects of DH on epigenetic changes in stress system related genes and on the physiological response to social stressors.

Methods: In the present study, conducted among 101 early adolescents (mean age = 11.

Exploring the perception of stress in childhood and early adolescence.

Stressful life experiences may jeopardize the healthy development of children. To improve interventions, more knowledge is needed on the perception of stress by children. In adults, stress is regarded as a state of low valence and high arousal.

The cumulative effect of chronic stress and depressive symptoms affects heart rate in a working population.

Background: Chronic stress and depressive symptoms have both been linked to increased heart rate (HR) and reduced HR variability. However, up to date, it is not clear whether chronic stress, the mechanisms intrinsic to depression or a combination of both cause these alterations. Subclinical cases may help to answer these questions.

Individual differences in environmental sensitivity at physiological and phenotypic level: Two sides of the same coin?

Young adolescents are hypothesized to differ in their environmental sensitivity, at both phenotypic (i.e., Sensory Processing Sensitivity [SPS]) and physiological (i.

Learning based Quality Indicator Aiding Heart Rate Estimation in Wrist-Worn PPG.

Technological advancements and miniaturization of wearable sensors have enabled long-term pervasive physiological monitoring. Wrist-worn photoplethysmography (PPG) sensors, although quite popular owing to their form factor, suffer from poor signal quality in ambulatory settings due to motion artifacts. This affects the reliable estimation of vital cardiac parameters, especially during motion/activities of daily living.

Twenty-Four-Hour Heart Rate Is a Trait but Not State Marker for Depression in a Pilot Randomized Controlled Trial With a Single Infusion of Ketamine.

Abnormalities of heart rate (HR) and its variability are characteristic of major depressive disorder (MDD). However, circadian rhythm is rarely taken into account when statistically exploring state or trait markers for depression. A 4-day electrocardiogram was recorded for 16 treatment-resistant patients with MDD and 16 age- and sex-matched controls before, and for the patient group only, after a single treatment with the rapid-acting antidepressant ketamine or placebo (clinical trial registration available on https://www.

Gastrointestinal symptoms in office workers are predicted by psychological distress and short sleep duration.

Objective: Gastrointestinal (GI) symptoms can be triggered by several lifestyle factors, including psychological distress, short sleep duration, and diet. It is poorly known which physiological mechanisms are involved, but the autonomic nervous system (as a key mediator of the stress response) is a likely candidate. We aimed to investigate the associations between selected lifestyle factors, measures of stress physiology, and GI symptoms.

Relationship Between Chronic Stress and Heart Rate Over Time Modulated by Gender in a Cohort of Office Workers: Cross-Sectional Study Using Wearable Technologies.

Background: Chronic stress is increasing in prevalence and is associated with several physical and mental disorders. Although it is proven that acute stress changes physiology, much less is known about the relationship between physiology and long-term stress. Continuous measurement of vital signs in daily life and chronic stress detection algorithms could serve this purpose.