Circulating rotaviral RNA in children with rotavirus antigenemia.

Background: Rotavirus antigenemia is a common phenomenon in children with rotavirus diarrhea, but information is scarce on aspects of this phenomenon, such as genotype specificity, presence of intact viruses and correlation between genomic RNA and antigen concentration. Such information may help in understanding rotavirus pathogenesis and eventually be useful for diagnosis, treatment and prevention.

Methods And Findings: Serum samples were collected from children who presented at hospitals with diarrhea.

Detection of human bocavirus in the cerebrospinal fluid of children with encephalitis.

We report 4 children with encephalitis associated with human bocavirus (HBoV) 1 or 2. All children were severely underweight, and 2 died; 1 of them had a matching HBoV2 nucleotide sequence isolated from serum and bocavirus like particles in the cerebrospinal fluid that were observed with electron microscopy. No further pathogens were detected in the cerebrospinal fluid of these patients.

Molecular characterization of VP7 gene of human rotaviruses from Bangladesh.

This study was carried out during July 2005-June 2006, to characterize rotaviruses circulating in Bangladeshi children less than 5 years attended a peri-urban hospital. The proportion of rotavirus diarrhea was 39.5%.

ARI situation in our country: aren't we oblivious of bronchiolitis in Bangladesh?

ARI/pneumonia has been the leading cause of morbidity and mortality in under five children for a long time. ARI control/Integrated Management of Childhood Illness (IMCI) program have been in progress in the country for more than a decade. There have been recent reports of outbreak of RSV bronchiolitis in the country.