Determining barriers to submitting antimicrobial-resistant isolates among hospitals in Texas Public Health Region 8.

Background: The Antimicrobial Resistance Laboratory Network (AR Lab Network) was developed by the CDC to detect emerging antimicrobial-resistant (AR) threats and prevent outbreaks. However, low submission rates of AR isolates limit the potential of the AR Lab Network to address antimicrobial resistance (AMR).

Aim: The aim of this study was to investigate barriers to submission of AR isolates in acute care hospitals (ACHs) and critical access hospitals (CAHs) within Texas Public Health Region 8 (PHR8) counties.

Patient-partner engagement at the Centre de recherche du CHUS in the Province of Québec, Canada: from an intuitive methodology to outreach after three years of implementation.

Background: Medical societies and funding agencies strongly recommend that patients be included as partners in research publications and grant applications. Although this "top-down" approach is certainly efficient at forcing this new and desirable type of collaboration, our past experience demonstrated that it often results in an ambiguous relationship as not yet well integrated into the cultures of either patients' or the researchers'. The question our group raised from this observation was: "How to generate a cultural shift toward a fruitful and long-lasting collaboration between patients and researchers? A "bottom-up" approach was key to our stakeholders.

Ultimate journey of the terminally ill: Ways and pathways of hope.

Objective: To better understand the role of hope among terminally ill cancer patients.

Design: Qualitative analysis.

Setting: A tertiary specialized cancer centre in Canada.

Impact of lamivudine-resistance mutations on entecavir treatment outcome in hepatitis B.

Background And Objective: Entecavir (ETV) is a potent inhibitor of viral replication in nucleos(t)ide analog (NA)-naive chronic hepatitis B patients with a very low rate of resistance (≤1.2%) over 5 years. The aim of this study was to assess the efficacy of ETV treatment in routine clinical practice and to investigate whether persistence of residual viral replication was the result of the emergence and selection of drug-resistant mutants.

[The affective experience of homelessness: from break-up to obsession.].

The qualitative analysis of 60 interviews of young homeless adults on the relational dimension of their experience allows a conceptualization of the construction of itineraries that takes into account two contradictory sides closely interrelated within the affective experience of homelessness: on one side, the break-up considered as essential to survival, on the other side, the obsessive preoccupation with relations denounced as ill-fated yet indispensable. One can see these two sides as the dynamic forces of a chain where refusal underlies the journeys of quest and erring.

Primum non nocere: could the health care system contribute to suffering? In-depth study from the perspective of terminally ill cancer patients.

Objective: To explore terminally ill patients' perceptions of their own suffering in order to describe, from these patients' perspective, some elements of health care providers' response to suffering.

Design: Qualitative study using content analysis methods suited to a grounded theory approach.

Setting: Teaching and nonteaching hospital oncology clinics, palliative care services (both ambulatory and in-unit), and family practices.

The nature of suffering and its relief in the terminally ill: a qualitative study.

The essential mandate of medicine is the relief of suffering. However, the quest for an integrated model towards a conceptualization of suffering is still ongoing and empirical studies are few. Qualitative inquiry using 31 in-depth interviews and content analysis was carried out between 1999 and 2001 in 26 patients diagnosed with terminal cancer.