Heterogeneity of serum basal C peptide levels amongst Arab patients with diabetes mellitus.

Thirty-four Arab patients with history of diabetes mellitus but without history of ketoacidosis (Group 2), and 16 Arab patients with history of diabetes mellitus and ketoacidosis (Group 1) were studied. They were compared with 15 healthy control subjects and were further broken down according to sex and type of therapy. Fasting serum C-peptide, glucose and glycosylated haemoglobin levels were measured in all subjects.

Excess body fat distribution and glucose homeostasis in obese Arab women.

The relationship of body fat distribution to glucose intolerance and non-insulin-dependent diabetes mellitus in Arab women was studied in 102 obese non-diabetic and 40 obese women with diabetes. The obese women underwent a glucose tolerance test. Linear regression analysis revealed a significant correlation between the waist/hip ratio and the plasma glucose concentration at 120 min.

A longitudinal study of insulin antibodies and anti-insulin cytotoxicity in type I diabetes mellitus.

Insulin antibodies and T-cell lymphocyte cytotoxic reactivity against insulin and its related peptides were studied longitudinally in 3 groups of patients with type I diabetes mellitus (DM). Group 1 patients were those in whom the diagnosis was made within 1 week of the initiation diagnosis. They were subdivided into those receiving MC porcine (A) or MC bovine (B) insulin.

Comparative evaluation for pollens and mite extract skin tests.

A study of 105 subjects with a history of atopy was conducted. The skin test was used as screening method and the specific IgE as reference test. The results of the mite extract skin test were compared with those of pollens.

Some demographic and therapeutic features of diabetes mellitus in Kuwait.

A survey of all consecutive visits to all diabetic clinics in Kuwait over a period of 4 months yielded 1,266 male and 1,838 female Kuwaiti patients. Their age structure analysis revealed percent frequencies of 1.25, 15.

The human cellular immune response to insulin: a study in unexposed control subjects and type I diabetic patients on acute and chronic treatment.

Using a cellular cytotoxicity assay, we have investigated the antigenicity of pharmaceutical insulins and of highly purified insulin constituents (unformulated monocomponent (MC) insulin, insulin B-component and C-peptide) in control, insulin naive, subjects and in three groups of type I diabetic patients. These were: Group 1, newly diagnosed patients receiving either porcine or bovine MC insulins for less than one week; Group 2, established patients receiving porcine or bovine MC insulin for 2-6 years; Group 3, established patients receiving conventional bovine insulin for 2-6 years, and tested within two weeks of switching to either porcine or bovine MC insulins. In control subjects, there was a higher incidence of cytotoxic reactions with beef (72%) than with porcine (33%) pharmaceutical preparations (p less than 0.

Periarthritis: another duration-related complication of diabetes mellitus.

The association between periarthritis of the shoulder and diabetes mellitus is well recognized. A study of 100 hospitalized patients with diabetes was performed, comparing them with 100 control subjects. The mean +/- SEM age of the subjects was 47 +/- 2 yr.

Prolactin in seminal fluid.

Prolactin appears to modulate male reproduction by regulating hormone receptor levels in the testis and accessory sex organs and by facilitating spermatozoal biochemical processes associated with capacitation. A large portion of immunoreactive prolactin (iPRL) seems to be transported from blood to semen via the accessory sex organs and takes several days to make this transition. The iPRL in semen is heterogeneous in size and a unique portion may be associated with spermatozoa.

Medullary carcinoma of the thyroid masquerading as idiopathic vocal cord paralysis.

The following conclusions may be drawn as a result of our study: 1. Serum calcitonin by radioimmunoassay proved to be the only valid preoperative indicator in a case of medullary carcinoma of the thyroid occurring with vocal cord paralysis. This test should be considered in all cases of idiopathic recurrent laryngeal nerve paralysis, especially when obscure thyroid pathology is suspected.

Size heterogeneity of immunoreactive prolactin in stored semen and seminal plasma.

The difference between semen and seminal plasma immunoreactive human prolactin (iPRL) correlates with sperm count. Seminal plasma separated from sperm before freezing (SPB), after freezing (SPA), and serum were fractionated by G100 Sephadex chromatography. SPA contained four different molecular weight fractions of iPRL.

The effect of freezing and storage on seminal immunoreactive prolactin.

Thirteen subjects were studied to compare changes in seminal immunoreactive prolactin produced by storage and freezing of semen and seminal plasma separated within 2 hours of ejaculation. Seminal prolactin was significantly higher in semen than in seminal plasma (paired t test, t = 3.29, p less than 0.

Maternal glycemia and birth weight.

A study of 96 high-risk, but uneventful pregnancies was performed. Overt hyperglycemia was excluded after 24 weeks of gestation by fasting serum glucose >110 mg, serum glucose of >140 mg two hours after a large breakfast (group 1, 44 subjects) or >140 mg two hours after a standard glucose load (group 2, 52 subjects). A significant linear correlation between the two-hour postprandial serum glucose and birth weight was found in group 1 (r = 0.

Correlations between seminal radioimmunoreactive prolactin, sperm count, and sperm motility in prevasectomy and infertility clinic patients.

Semen samples were collected from 50 prevasectomy patients and 43 infertility clinic patients. Various parameters were measured, including semen radioimmunoreactive prolactin (rPRL) levels. Linear correlations were tested between the measured parameters, and a significant correlation was found between semen rPRL concentration and sperm count for both the prevasectomy (r = 0.

Comparison of prolactin levels in human semen and seminal plasma.

Semen samples were collected from 35 men and the levels of prolactin in semen and seminal plasma were measured. There was no significant difference in prolactin concentrations between the two fluids (t = 0.333, P greater than 0.

Seminal immunoreactive prolactin before and after vasectomy.

Seminal fluid was assayed for prolactin by radioimmunoassay in eleven healthy males 8-12 weeks following vasectomy. The results were compared with those obtained in 34 age matched subjects prior to undergoing vasectomy. The mean values (+/- 1 SD) for prolactin were similar (postvasectomy = 11.

Inherent ranges of seminal prolactin in pre- and postvasectomy subjects.

Seminal immunoreactive prolactin (i prolactin) was studied in 14 healthy subjects, ages 31 +/- 2 SEM, before and after undergoing elective vassectomy for birth control. Seminal plasma was separated within 2 hours of ejaculation, and prolactin was measured in duplicate by radioimmunoassay. The difference between the prevasectomy (mean +/- SEM 11.