Using Logistics Companies to Regulate Online Food Safety: Feasibility and Impacts Based on Social Cogovernance in China.

China's traditional governance model, featuring localized management by local governments, has been unable to effectively manage the increasing cross-regional flow of food safety risks caused by the emerging trends in online food consumption. This weakness highlights the urgent need to reform the online food safety regulation mechanism. To support this effort, this study uses the social cogovernance framework to investigate the effects of regulation by logistics companies on the behavioral strategy choices of sellers and the social cogovernance level.

Generation and propagation of circular Airy derivative beams carrying rotationally-symmetric power-exponent-phase vortices.

In this paper, the circular Airy derivative beams carrying rotationally-symmetric power-exponent-phase vortices are proposed for the first time, whose evolutionary properties are explored by theoretical analysis as well as experimental verification. The intensity and phase distributions of this kind of beam can be flexibly modulated by controlling its parameters such as derivative order, topological charge, and power order. Intriguingly, the evolution of such beams with different fractional topological charges is also investigated in detail by means of phase singularities distribution.

Tunable Bessel beam generator based on a 3D-printed helical axicon on a fiber tip.

We demonstrate a tunable and fully enclosed fiber-based Bessel beam generator that has the potential for applications in a tough environment. This generator consists of a few-mode fiber (FMF), a short section of graded index fiber (GIF), and a 3D-printed helical axicon. The FMF provides tunable modes that carry an orbital angular momentum (OAM).

Nonparaxial propagation and the radiation forces of the chirped circular Airy derivative beams.

In this paper, we investigate the nonparaxial propagation dynamics of the chirped circular Airy derivative beams (CCADBs) based on vector angular spectrum method. In the case of nonparaxial propagation, the CCADBs still maintains excellent autofocusing performances. Derivative order and chirp factor are two important physical quantities of the CCADBs to regulate the nonparaxial propagation characteristics, such as focal length, focal depth and K-value.

Tunable mode convertor based on fiber Bragg grating inscribed in graded-index nine-mode fiber.

A tunable mode convertor is experimentally demonstrated based on a fiber Bragg grating (FBG), which is fabricated in a graded-index nine-mode fiber by using a femtosecond laser. Nine linearly polarized (LP) modes were excited and the coupling efficiency of them can reach 90%. By adjusting the polarization controller, the ±1st-, ±2nd-, ±3rd-, and ±4th-order orbital angular momentum (OAM) modes were excited, which means the OAM tuning of 0-±1ℏ, 0-±2ℏ, 0-±3ℏ, and 0-±4ℏ were achieved.

Deep learning assisted contrast-enhanced CT-based diagnosis of cervical lymph node metastasis of oral cancer: a retrospective study of 1466 cases.

Objectives: Lymph node (LN) metastasis is a common cause of recurrence in oral cancer; however, the accuracy of distinguishing positive and negative LNs is not ideal. Here, we aimed to develop a deep learning model that can identify, locate, and distinguish LNs in contrast-enhanced CT (CECT) images with a higher accuracy.

Methods: The preoperative CECT images and corresponding postoperative pathological diagnoses of 1466 patients with oral cancer from our hospital were retrospectively collected.

Focused vortex beam generator suitable for optical fiber spanners in a complex liquid environment.

We experimentally demonstrated an all-fiber focused vortex beam (FVB) generator which was prepared by milling a spiral zone plate (SZP) on the Au-coated end face of a hybrid fiber by focused ion beam (FIB). In this generator, the fundamental modes propagating in the hybrid fiber are focused while being modulated into high-order orbital angular momentum (OAM) mode by the SZP at the end face. The focus length and topological charge were designed and then were both theoretically and experimentally verified.

Roles of Mitochondria in Oral Squamous Cell Carcinoma Therapy: Friend or Foe?

Oral squamous cell carcinoma (OSCC) therapy is unsatisfactory, and the prevalence of the disease is increasing. The role of mitochondria in OSCC therapy has recently attracted increasing attention, however, many mechanisms remain unclear. Therefore, we elaborate upon relative studies in this review to achieve a better therapeutic effect of OSCC treatment in the future.

Direct generation of orbital angular momentum in orthogonal fiber Bragg grating.

We experimentally demonstrated an all-fiber reflective orbital angular momentum (OAM) generator based on orthogonal fiber Bragg grating (OFBG). The OFBG is formed by using a femtosecond laser to prepare two fiber Bragg gratings with a certain spacing in orthogonal planes. The ±1st- and ±2nd-order OAM modes were directly excited in this OFBG, and the chirality of the OAM modes depends on the relative positions of the two FBGs.

High-order orbital angular momentum mode conversion based on a chiral long period fiber grating inscribed in a ring core fiber.

A chiral long period fiber grating (CLPFG) was designed according to the phase-matching condition and conservation law of angular momentum, and was inscribed in a ring core fiber (RCF). This CLPFG was used to directly excite the ±2- and ±3-order orbital angular momentum (OAM) modes. The coupling efficiency of the OAM mode is up to 98.

Vascular iliac myofascial flap to repair compound defect of the jaw.

The vascular iliac myofascial flap is a compound flap with the deep circumflex iliac artery (DCIA) as the vascular pedicle, carrying the iliac bone and parts of the internal oblique, external oblique and muscle-fascial tissue that cover the surface of the iliac crest and inside the iliac bone. The aim of this study was to advocate a feasible surgical strategy for maxillofacial surgeons through our review of clinical applications and to improve the quality of life of patients after the operation. In recent years, Stomatology Hospital of Wuhan University has performed dozens of vascularized iliac myofascial flaps, not only to repair jaw defects but also to complete the repair of intraoral soft tissue defects.

Histone methyltransferase KMT2D cooperates with MEF2A to promote the stem-like properties of oral squamous cell carcinoma.

Background: Epigenetic reprogramming is involved in multiple steps of human cancer evolution and is mediated by a variety of chromatin-modifying enzymes. Specifically, the histone lysine methyltransferase KMT2D is among the most frequently mutated genes in oral squamous cell carcinoma (OSCC). However, the mechanisms by which KMT2D affects the development of OSCC remain unclear.

Orbital Angular Momentum Mode Sensing Technology Based on Intensity Interrogation.

A novel optical fiber sensing technology based on intensity distribution change in orbital angular momentum (OAM) mode is proposed and implemented herein. The technology utilizes a chiral long-period fiber grating (CLPFG) to directly excite the 1st-order OAM (OAM) mode. The intensity changes in the coherent superposition state between the fundamental mode and the OAM mode at the non-resonant wavelength of the CLPFG is tracked in order to sense the external parameters applied to the grating area.

Femtosecond laser inscribed helical long period fiber grating for exciting orbital angular momentum.

A method employing femtosecond lasers to inscribe helical long period fiber grating (HLPFG) for exciting orbital angular momentum (OAM) of light is experimentally demonstrated. In this method, the refractive index modulation (RIM) of HLPFG is realized by three-dimensional translation of a fiber without rotation, indicating better stability, repeatability and flexibility. The coupling efficiency can be customized by varying the radius of the helical RIM, except laser energy.

Ultra-dense perfect optical orbital angular momentum multiplexed holography.

Optical orbital angular momentum (OAM) has been recently implemented in holography technologies as an independent degree of freedom for boosting information capacity. However, the holography capacity and fidelity suffer from the limited space-bandwidth product (SBP) and the channel crosstalk, albeit the OAM mode set exploited as multiplexing channels is theoretically unbounded. Here, we propose the ultra-dense perfect OAM holography, in which the OAM modes are discriminated both radially and angularly.

Enantioselective Rauhut-Currier-Type 1,6-Conjugate Addition of Methyl Vinyl Ketone to para-Quinone Methides.

An unprecedented Rauhut-Currier-type 1,6-conjugate addition has been developed. With chiral cyclohexane-based phosphine-amide catalyst 3 h, the 1,6-conjugate reaction has been achieved to produce chiral diarylmethine compounds in excellent yields (91-99 %) and enantioselectivities (92-98 % ee).

A distal methyl substituent attenuates mitochondrial protein synthesis inhibition in oxazolidinone antibacterials.

Oxazolidinone analogs bearing substituted piperidine or azetidine C-rings are described. Analogs with a methyl group at the 3-position of the azetidine ring or the 4-position of the piperidine ring exhibited reduced mitochondrial protein synthesis inhibition while retaining good antibacterial potency.

Oxazolidinones inhibit cellular proliferation via inhibition of mitochondrial protein synthesis.

The oxazolidinones are a relatively new structural class of antibacterial agents that act by inhibiting bacterial protein synthesis. The oxazolidinones inhibit mitochondrial protein synthesis, as shown by [35S]methionine incorporation into intact rat heart mitochondria. Treatment of K562 human erythroleukemia cells with the oxazolidinone eperezolid resulted in a time- and concentration-dependent inhibition of cell proliferation.