Publications by authors named "Luping Bu"

Article Synopsis
  • Maintaining balanced lipid levels is crucial for preventing lipotoxicity in tumors like colorectal cancer (CRC).
  • The RNA-binding protein HuR appears to enhance the expression of the vitamin D receptor (VDR), which helps regulate triglyceride (TG) and total cholesterol (TC) levels in CRC.
  • Targeting HuR could be a promising therapeutic strategy, as it affects VDR expression and lipid metabolism, ultimately influencing CRC growth.
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Colorectal cancer (CRC) is one of the most common malignant carcinomas worldwide with poor prognosis, imposing an increasingly heavy burden on patients. Previous experiments and epidemiological studies have shown that vitamin D and vitamin D-related genes play a vital role in CRC. Therefore, we aimed to construct a vitamin D-related gene signature to predict prognosis in CRC.

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Curcumin is a natural compound extracted from turmeric (Curcuma longa), which has been reported to be a promising anti‑cancer drug in various human cancers. However, the effects of combination treatment of curcumin with gemcitabine or docetaxel on pancreatic cancer remains elusive. In the present study, the combinatory effects of curcumin with either gemcitabine or docetaxel on the proliferation, apoptosis, migration as well as invasion of PC cells were investigated.

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In this paper, we apply the detrended fluctuation analysis (DFA), local scaling detrended fluctuation analysis (LSDFA), and detrended cross-correlation analysis (DCCA) to investigate correlations of several stock markets. DFA method is for the detection of long-range correlations used in time series. LSDFA method is to show more local properties by using local scale exponents.

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