Publications by authors named "Luoyao Zhang"
BMC Complement Med Ther
July 2022
Article Synopsis
- The study investigates the potential protective effects of resveratrol against hyperlipidemia acute pancreatitis (HTG-AP) using a mouse model to understand the underlying mechanisms.
- Mice were fed normal chow or a high-fat diet (HFD) for six weeks, with some receiving resveratrol treatment to assess its impact on pancreatic injury and inflammation markers.
- The results show that resveratrol significantly reduced pancreatic damage, inflammation, and oxidative stress by inhibiting the NF-κB signaling pathway and improving gut microbiota, indicating its preventive role in HTG-AP.
Medicine (Baltimore)
February 2022
Article Synopsis
- Endoscopic submucosal dissection (ESD) is gaining popularity as a treatment for early esophageal cancer, but it carries a risk of esophageal stricture as a complication.
- The study analyzed 159 patients to identify key risk factors for esophageal stricture, finding that age over 60, a high neutrophil-to-lymphocyte ratio, a large mucosal defect, and specific cancer types significantly predict stricture risk.
- A nomogram model was developed to predict esophageal stricture with good accuracy (area under the curve 0.889), although further validation is needed to ensure its effectiveness in different patient populations.
