Publications by authors named "Luoxiang Qian"

Renal interstitial fibrosis (RIF) is a common pathway in chronic kidney disease (CKD) that ultimately leads to end-stage renal failure, worsening both glomerulosclerosis and interstitial fibrosis. Ten percent of the adult population in the world suffers from CKD, and as the ageing population continues to rise, it is increasingly regarded as a global threat-a silent epidemic. CKD has been discovered to be closely associated with both long noncoding RNAs (lncRNAs) and microRNAs (miRNAs), while the precise molecular processes behind this relationship are still unclear.

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Article Synopsis
  • * Key types of ncRNAs, such as microRNAs, long noncoding RNAs, and circular RNAs, are associated with protective and harmful effects in kidney diseases, including inflammation and fibrosis.
  • * The article explores the therapeutic potential of ncRNAs in kidney disease and their possible use as biomarkers, providing insights for treatment options in acute and chronic renal conditions.
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Synopsis of recent research by authors named "Luoxiang Qian"

  • - Luoxiang Qian's recent research focuses on the role of non-coding RNAs (ncRNAs) in the context of kidney diseases, highlighting their potential regulatory functions in both acute and chronic kidney conditions.
  • - The study emphasizes the significance of various types of ncRNAs, including microRNAs (miRNAs), long noncoding RNAs (lncRNAs), and circular RNAs (circRNAs), in influencing critical biological processes related to kidney health and disease.
  • - Findings suggest that ncRNAs possess therapeutic potential due to their involvement in anti-inflammatory, antiapoptotic, antifibrotic, and proangiogenic mechanisms, indicating a need for further exploration in clinical applications for kidney disease management.