Nine previously undescribed (1-9) and seven known (10-16) cycloartane-type triterpenoids were isolated and characterized from Combretum quadrangulare Kurz using physicochemical and spectroscopic methods. The absolute configurations of these compounds were determined through modified Mosher's method and quantum chemical calculation of electronic circular dichroism (ECD) and vibrational circular dichroism (VCD) spectra. Their inhibitory activities against PCSK9 secretion were assessed, and a plausible structure-activity relationship was delineated.
View Article and Find Full Text PDFThis study was aimed to investigate the chemical composition and biological activities of leaf and stem essential oils of Zanthoxylum acanthopodium DC. from Vietnam. Their chemical composition was analyzed by GC/MS.
View Article and Find Full Text PDFNew essential oils (EOs) extracted from different parts of two species ( and ) from Vietnam were investigated for their chemical composition, anti-inflammatory and cytotoxic activity. Sixty-nine total compounds were identified in the EOs by GC/MS. The major constituent of the leaf, fruit, and root EOs from was β-caryophyllene (71.
View Article and Find Full Text PDFis a traditional medicinal herb used in Vietnam and several other countries. However, the skin-protective properties of ethanol extract (As-EE) have not been evaluated. Human keratinocytes form the outermost barrier of the skin and are the main target of ultraviolet (UV) radiation.
View Article and Find Full Text PDFJuss. is a deciduous shrub that mainly grows in Asia. Despite studies of other species for treatment of various diseases, Juss.
View Article and Find Full Text PDFNgoc & L. V. Dung, a new species from the Central highland of Vietnam, is described and illustrated.
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