The immune response of pregnant sow after vaccination with crude fimbriae (F4) extracts vaccine and immunoprotection of nursery pig against pathogenic E. coli (F4ETEC).

Background: Neonatal and post-weaning diarrhea is a concern disease caused by enterotoxigenic Escherichia coli fimbriae F4 (F4ETEC) in pig farms. Diarrhea outbreaks are often severe and costly due to the high prevalence and spread of the disease within the same herd. Vaccine is one of strategic solution in protecting pig against F4ETEC infection in particular pig farm.

Feasibility of crude F4 fimbriae extract as a vaccine candidate for preventing -induced diarrhea in piglets.

Background And Aim: Enterotoxigenic (ETEC) poses a substantial risk of neonatal diarrhea and post-weaning diarrhea among piglets, with F4 ETEC strains emerging as a particularly challenging issue within the pig farming industry. This study aimed to introduce a straightforward approach for generating a crude extract of F4 fimbriae that shows promise as an antigenic determinant for potential vaccination strategies.

Materials And Methods: A crude F4 fimbriae extract was obtained from F4 ETEC using a combination of heat shock and homogenization techniques.

Antibiotic resistant Escherichia coli from diarrheic piglets from pig farms in Thailand that harbor colistin-resistant mcr genes.

Antibiotic-resistant Escherichia coli is one of the most serious problems in pig production. This study aimed to determine the antibiotic susceptibility and genotypes profiles of diarrhoeagenic E. coli that causes diarrhea in piglets.