Publications by authors named "Luobing Tian"
Although previous studies have proposed predictive models of gestational diabetes mellitus (GDM) based on maternal status, they do not always provide reliable results. The present study aimed to create a novel model that included ultrasound data of maternal fat distribution and serum inflammatory factors. The clinical data of 1,158 pregnant women treated at Tangshan Gongren Hospital and eight other flagship hospitals in Tangshan, including the First Hospital of Tangshan Gongren Hospital group, Ninth Hospital of Tangshan Gongren Hospital group, Tangshan Gongren Hospital group rehabilitation hospital, Tangshan railway central hospital, Tangshan Gongren Hospital group Fengnan hospital, Tangshan Gongren Hospital group Qianan Yanshan hospital, Tangshan Gongren Hospital group Qianxi Kangli hospital and Tangshan Gongren Hospital group Jidong Sub-hospital, were analyzed following the division of subjects into GDM and non-GDM groups according to their diagnostic results at 24-28 weeks of pregnancy.
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- Cognitive impairment is a common yet often overlooked issue in diabetes, leading to problems with memory and learning.
- A study using a diabetic rat model showed that vildagliptin, a drug that helps control blood sugar, can prevent memory issues and reduce neuron death in the brain.
- The research suggests that vildagliptin works by influencing certain proteins and signaling pathways that protect against cognitive decline in diabetes.
Article Synopsis
- The study investigates the link between specific chromosome 1p13 variants and the risk of developing peripheral artery disease (PAD) in Chinese patients with type 2 diabetes.
- It analyzes the genetic polymorphisms rs599839, rs646776, and rs12740374 in a group of 882 diabetes patients, finding lower frequencies of certain alleles and genotypes in those with PAD compared to those without.
- The results suggest that these genetic variations may serve as protective factors against PAD in this population, indicating a potential genetic influence on disease susceptibility.
Type 2 diabetes mellitus (T2DM) is a complex metabolic disorder caused by the interaction of environmental factors and multiple genes. The genetic background of T2DM is complex and remains to be fully elucidated. MicroRNAs (miRNAs) are negative regulators of gene expression and several miRNAs are associated with the development of T2DM.
View Article and Find Full Text PDFThe aim of this study was to observe and investigate the clinical efficacy of an intravenous drip of isosorbide mononitrate (ISMN) for the treatment of angina pectoris in coronary heart disease. A total of 102 patients with angina pectoris in coronary heart disease were divided into two groups. For the treatment group (n=51), 20 mg ISMN was added to 250 ml 0.
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- The study investigated the connection between specific genetic variants (SNPs rs10757274 and rs10757278) and the risk of developing peripheral arterial disease (PAD) in a Han Chinese population, particularly in the context of existing coronary artery disease.
- Researchers compared the genotypes of 420 PAD patients with 418 control subjects, using logistic regression to control for factors like age, sex, and lifestyle.
- Results showed that certain genetic variants were associated with a higher risk of PAD in individuals under 65, but this association was less clear in those aged 65 and older.