Publications by authors named "LuoYong Jiang"
Article Synopsis
- The study aimed to visualize the spatial distribution of femoral head necrosis using a new measurement method called the longitude and latitude division system (LLDS).
- Researchers analyzed CT data from 108 hips with non-traumatic osteonecrosis, creating a computer-aided design tool to visualize necrotic lesions in both 2D and 3D heat maps.
- Results indicated that the LLDS has high reliability, revealing concentrated clustering of necrotic lesions in specific regions of the femoral head, particularly in type C lesions, which helps in understanding the differences between subtypes C1 and C2.
Article Synopsis
- The study investigated how patients who had periacetabular osteotomy (PAO) surgery walked after the operation, focusing on two different fixation methods: iliac screw (IS) and transverse screw (TS).
- Twelve patients with hip dysplasia participated, and their preoperative and postoperative gait data were analyzed to assess biomechanical aspects using musculoskeletal models and finite element analysis.
- Post-surgery, patients showed improved but still suboptimal gait characteristics compared to healthy individuals, with differences in hip movement and muscle forces; however, the predicted yield loads for both fixation methods were adequate for normal walking loads.
Objective: Circular RNAs (circRNAs) have been extensively implicated in osteoarthritis (OA) progression. Therefore, this study explores the impact of hsa_circ_0004662 on OA progression and the related molecular mechanism.
Methods: Human articular chondrocyte injury was induced by IL-1β to construct the OA model in vitro.
Background: The difference between MRI (Magnetic resonance imaging)-R2* and T2 mapping sequences regarding their superiority in the detection of microstructural cartilage changes in knees with limited ROM (range of motion) was unknown.
Methods: Twenty male cynomolgus monkeys (mean age: 10.65 ± 0.
Article Synopsis
- Osteoarthritis (OA) is a common degenerative joint disease where inflammation is crucial for its development; CAPE, a natural flavonoid, shows promise in reducing this inflammation.
- In studies with IL-1β-stimulated chondrocytes and rat models, CAPE decreased harmful enzymes and inflammatory markers, while promoting substances that help maintain cartilage structure.
- The findings suggest that CAPE could be a potential treatment or preventative measure for OA, as it effectively protects cartilage and slows disease progression.
Long noncoding RNA (lncRNA) maternally expressed 8, small nucleolar RNA host gene (MEG8) has been widely reported for its pro-proliferative, anti-apoptotic and anti-inflammatory effects in diverse diseases. The aim of the present study was to investigate the effects and underlying mechanism of MEG8 on IL-1β-stimulated human osteoarthritis (OA) chondrocytes. C28/I2 chondrocytes were cultured under the stimulation of IL-1β to establish a cellular model of OA.
View Article and Find Full Text PDFSubtalar arthroereisis has been proved to be an efficient method for correcting flexible adult flatfoot. However, the optimal sinus tarsi implant is still debated and yet to be determined. In the present study, we compared the biomechanical effects of type I and II sinus tarsi implants in stage II adult-acquired flatfoot deformity (AAFD).
View Article and Find Full Text PDFFrozen shoulder is a chronic condition characterized by pain in the shoulder and restriction of movements in all directions. Some patients are left with long-term limitation of shoulder joint activity with various severities, which results in reduced quality of life. Currently, there is a paucity of literature on the molecular biology of frozen shoulder, and the molecular biological mechanism for periarthritis-induced limitation of shoulder joint movements remains unclear.
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