Publications by authors named "Luo Zi-Yan"

Article Synopsis
  • The study evaluates the safety and feasibility of totally robotic gastrectomy (TRG) compared to totally laparoscopic gastrectomy (TLG) in patients with gastric cancer, highlighting advancements in minimally invasive surgery.
  • A total of 346 patients were analyzed, with results showing that the TRG group had longer total operation times but shorter digestive tract reconstruction times, along with less blood loss and more lymph nodes retrieved compared to the TLG group.
  • The findings conclude that TRG is a safe and effective alternative to TLG, showcasing advantages in surgical ergonomics and overall invasiveness without significant differences in postoperative complications.
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Background: Total gastrectomy for carcinoma in the remnant stomach (CRS) remains a technically demanding procedure. Whether robotic surgery is superior, equal, or inferior to laparoscopic surgery in patients with CRS is unclear. This study was designed to compare the efficacy and safety of robotic total gastrectomy (RTG) and laparoscopic total gastrectomy (LTG) for the treatment of CRS.

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Background: This study was designed to compare the postoperative complications after Robotic total gastrectomy (RTG) and robotic distal gastrectomy (RDG) and to systematically evaluate the safety and feasibility of RTG for the treatment of gastric cancer (GC).

Methods: Patients with GC who underwent RTG or RDG for curative intent between March 2010 and August 2019 were analyzed. We used propensity score matching (PSM) to reduce selection bias.

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Article Synopsis
  • * Data were collected from 899 patients over a span of nine years, showing that a specific number of surgeries are required for surgeons to become proficient, with 22 patients for distal and 20 for total gastrectomy regarding operation time.
  • * Results indicate that as surgeons gain experience, both operation times and postoperative complications improve significantly, suggesting that experience in one type of robotic surgery can enhance skills in another.
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Background: In this study, we investigated the incidence and risk factors for postoperative complications after robotic gastrectomy (RG) in patients with gastric cancer.

Methods: A total of 817 patients who underwent RG for gastric cancer between March 2010 and August 2019 were analyzed retrospectively. Postoperative complications were categorized according to the Clavien-Dindo classification, and possible risk factors were evaluated.

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Background: The robotic surgical system has several technical advantages over laparoscopic instruments. The technical feasibility and safety of robotic gastrectomy (RG) for gastric cancer have been reported by increasing number of studies. However, the long-term survival and recurrence outcomes after RG for locally advanced gastric cancer (AGC) have seldom been reported.

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Background: Bmi-1, the B cell-specific moloney murine leukemia virus insertion site 1, is a member of the Polycomb-group (PcG) family and acts as an oncogene in various tumors; however, its expression related to the prognosis of pediatric patients with acute lymphoblastic leukemia (ALL) has not been well studied.

Methods: The Bmi-1 expression levels in the bone marrow of 104 pediatric ALL patients and 18 normal control subjects were determined by using qRT-PCR. The association between the Bmi-1 expression and the clinicopathological characteristics of pediatric ALL patients was analyzed, and the correlation between Bmi-1 and the prognosis of pediatric ALL was calculated according to the Kaplan-Meier method.

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Objective: To investigate the expression of miR-181a in AML cell lines and explore its effect on cell proliferation.

Methods: The expression of miR-181a in AML cell lines (NB4,HL-60,K562 and MV-4-11) was detected by quantiative polymerase chain reation(qPCR). Moreover, the cell proliferation and cell cycle were evaluated in several cell lines (HL60, NB4 and K562) by using CCK-8 and flow cytometry after the imitative transfection with miR-181a.

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