Micropollutants (MPs) in aquaculture water are directly related to human health, but largely overlooked. The conventional water treatment technologies could not effectively remove MPs, and new technologies have been pursued with high MP removal rate, low cost and small footprint. This paper reported the first endeavor of using layer-by-layer (LBL) hollow fiber (HF) nanofiltration (NF) membranes to treat real aquaculture water.
View Article and Find Full Text PDFBackground: Despite extensive knowledge of tuberculosis (TB) and its control, there remains a significant gap in understanding the comprehensive impact of the COVID-19 pandemic on TB incidence patterns. This study aims to explore the impact of COVID-19 on the pattern of pulmonary tuberculosis in China and examine the application of time series models in the analysis of these patterns, providing valuable insights for TB prevention and control.
Methods: We used pre-COVID-19 pulmonary tuberculosis (PTB) data (2007-2018) to fit SARIMA, Prophet, and LSTM models, assessing their ability to predict PTB incidence trends.
Effective livestock manure management is crucial for carbon neutrality. Scientific accounting methods and integrated management strategies can help guide reductions in carbon emissions and promote green development. To reduce greenhouse gas emissions by livestock manure, this study analyzed current accounting systems and focused on the complete chain of "collection-treatment-storage-use-returning" of manure based on the theoretical framework of greenhouse gas emissions accounting in the IPCC 2019 Guidelines.
View Article and Find Full Text PDFBackground: This research endeavors to scrutinize the temporal trends and global burden of cardiovascular diseases (CVDs) associated with ambient particulate matter (PM) pollution spanning from 1990 to 2019.
Methods: Age-standardized death rates (ASDRs) and age-standardized disability-adjusted life years (DALYs) for CVDs, as well as their estimated annual percentage changes (EAPCs), were calculated using data from the Global Burden of Disease Study 2019 (GBD 2019).
Results: The global ASDR and age-standardized DALYs due to CVDs associated with PM pollution increased from 1990 to 2019, with a higher increase in males.
Sensors (Basel)
September 2024
The efficient detection of leakages in water distribution networks (WDNs) is crucial to ensuring municipal water supply safety and improving urban operations. Traditionally, machine learning methods such as Convolutional Neural Networks (CNNs) and Autoencoders (AEs) have been used for leakage detection. However, these methods heavily rely on local pressure information and often fail to capture long-term dependencies in pressure series.
View Article and Find Full Text PDFBackground: Metabolic reprogramming plays a pivotal role in cancer progression, contributing to substantial intratumour heterogeneity and influencing tumour behaviour. However, a systematic characterization of metabolic heterogeneity across multiple cancer types at the single-cell level remains limited.
Methods: We integrated 296 tumour and normal samples spanning six common cancer types to construct a single-cell compendium of metabolic gene expression profiles and identify cell type-specific metabolic properties and reprogramming patterns.
J Environ Manage
November 2024
Soil contamination with heavy metals (HMs) is still a global issue. The maintenance of long-term stability of HMs in soil during immobilization remediation is a challenge. Microwave (MW) technology can promote the immobilization of HMs in the form of crystals and minerals, thus enhancing their resistance of corrosion.
View Article and Find Full Text PDFLow-coordination platinum-based nanocrystals emanate great potential for catalyzing the oxygen reduction reactions (ORR) in fuel cells, but are not widely applied owing to poor structural stability. Here, several PtCu nanocrystals (PtCu NCs) with low coordination numbers were prepared via a facile one-step method, while the desirable catalyst structures were easily obtained by adjusting the reaction parameters. Wherein, the PtCu NCs catalyst with abundant twin boundaries and high-index facets displays 15.
View Article and Find Full Text PDFObjectives: Congenital hypogonadotropic hypogonadism (CHH) is a rare condition caused by a defect in the production, secretion or action of gonadotropin-releasing hormone. The absence of puberty and varying degrees of gonadotropic deficiency are common symptoms of this disorder. Heterogeneity exists in the clinical presentation of the different clinical subtypes and multiple genes have been implicated in CHH.
View Article and Find Full Text PDFFront Aging Neurosci
August 2024
The blood-brain barrier is known to consist of a variety of cells and complex inter-cellular junctions that protect the vulnerable brain from neurotoxic compounds; however, it also complicates the pharmacological treatment of central nervous system disorders as most drugs are unable to penetrate the blood-brain barrier on the basis of their own structural properties. This dramatically diminished the therapeutic effect of the drug and compromised its biosafety. In response, a number of drugs are often delivered to brain lesions in invasive ways that bypass the obstruction of the blood-brain barrier, such as subdural administration, intrathecal administration, and convection-enhanced delivery.
View Article and Find Full Text PDFBackground: Rosacea has a high incidence, significantly impacts quality of life, and lacks sufficient diagnostic techniques. This study aimed to investigate the feasibility of laser speckle contrast imaging (LSCI) for measuring facial blood perfusion in patients with rosacea and to identify differences in blood flow among various facial regions associated with different rosacea subtypes.
Methods: From June to December 2023, 45 patients were recruited, with 9 excluded, leaving 36 subjects: 12 with erythematotelangiectatic rosacea (ETR), 12 with papulopustular rosacea (PPR), and 12 healthy controls.
Peroxymonosulfate (PMS) based on heterogeneous catalytic reaction was a promising advanced oxidation process (AOP) to remove refractory contaminants. However, the contaminant degradation efficiency was challenged by the limited number of catalytic active site and low capacity for durable electron transfer. In this study, cobalt-doped manganese-iron oxides (CoMnFeO) rich in oxygen vacancy (Ov) were synthesized using a microwaved hydrothermal method and applied to activate PMS for bisphenol A (BPA) degradation, which achieved the complete removal of BPA within 30 min.
View Article and Find Full Text PDFBackground: The clinical applications of endoscope-assisted transoral release for irreducible atlantoaxial dislocations are limited. This study aimed to investigate the clinical effect and prognostic factors of traditional and endoscope-assisted transoral release, as well as posterior reduction and fixation, in treating irreducible atlantoaxial dislocations.
Materials And Methods: We conducted a retrospective study on 59 patients with irreducible atlantoaxial dislocation who underwent either traditional or endoscope-assisted transoral release, posterior fixation, and fusion between January 2018 and January 2023.
The aim of the present study was to explore the molecular mechanisms by which miR-193b-3p-trans-fected bone marrow mesenchymal stem cells (BMSCs) transplantation improves neurological impairment after traumatic brain injury (TBI) through sphingosine-1-phosphate receptor 3 (S1PR3)-mediated regulation of the phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin (PI3K/AKT/mTOR) pathway at the cellular and animal levels. BMSCs were transfected with miR-193b-3p. A TBI cell model was established by oxygen-glucose deprivation (OGD)-induced HT22 cells, and a TBI animal model was established by controlled cortical impact (CCI).
View Article and Find Full Text PDFThere are currently almost no ternary platinum-based nanosheets used for acidic oxygen reduction reactions (ORR) due to the difficulty in synthesizing ternary nanosheets with high Pt content. In this work, several ultrathin platinum-palladium-copper nanosheets (PtPdCu NSs) with a thickness of around 1.90 nm were prepared via a microwave heating-assisted method.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
July 2024
Purpose: To evaluate the burden of type 2 diabetes (T2D) among adolescents (15-24 years old) from 1990 to 2019.
Methods: The age-standardized incidence rate (ASIR) and disability-adjusted life years (DALYs) rate of adolescents were analyzed according to age, sex, geographical location, and sociodemographic index (SDI). The estimated annual percentage change (EAPC) was estimated to quantify the trends.
Avian astrovirus can infect a variety of poultry species and cause viral diarrhea, with a wide epidemic range strong pathogenicity and a high incidence. Among them, Duck astrovirus 3(DAstV-3), Duck astrovirus 4(DAstV-4), Goose astrovirus 1(GoAstV-1) and Goose astrovirus 2(GoAstV-2) are four types of astroviruses newly discovered in waterfowl in recent years. In order to realize the rapid detection of these four kinds of waterfowl stellate viruses, specific primers and probes were engineered to target a highly conserved region of ORF1b gene of DAstV-3, GoAstV-1 and GoAstV-2 and the ORF2 gene of DAstV-4, and a quadruple fluorescence quantitative RT-PCR method was developed.
View Article and Find Full Text PDFObjectives: Opioid nonadherence represents a significant barrier to cancer pain treatment efficacy. However, there is currently no effective prediction method for opioid adherence in patients with cancer pain. We aimed to develop and validate a machine learning (ML) model and evaluate its feasibility to predict opioid nonadherence in patients with cancer pain.
View Article and Find Full Text PDFJ Colloid Interface Sci
November 2024
Optimizing the pore structure and its interaction with the electrolytes was vital for enhancing the performance of supercapacitors based on the electrical double layer mechanism. In this study, graded porous carbon material (STP) with outstanding properties was prepared by adjusting the activation temperature and KOH dosage in the microwave pyrolysis process of sargassum thunbergii. The results demonstrated that better electrochemical performance was obtained when 1 M NaNO was used as electrolyte and STP-800-3 was employed as electrode material, attributed to its excellent specific surface area (SSA) of 2011.
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