Publications by authors named "Lunhua Ge"
Antibiotic-induced dysbiosis in the fish gut causes significant adverse effects. We use fecal microbiota transplantation (FMT) to accelerate the restoration of florfenicol-perturbed intestinal microbiota in koi carp, identifying key bacterial populations and metabolites involved in the recovery process through microbiome and metabolome analyses. We demonstrate that florfenicol disrupts intestinal microbiota, reducing beneficial genera such as Lactobacillus, Bifidobacterium, Bacteroides, Romboutsia, and Faecalibacterium, and causing mucosal injuries.
View Article and Find Full Text PDFArticle Synopsis
- Bacterial intestinal inflammation is a common issue in cultured fish, specifically in tongue sole (Cynoglossus semilaevis), which was studied after exposure to Shewanella algae.
- The research revealed significant changes in intestinal permeability, highlighted by wider intercellular spaces and an increase in mucous cells following the infection.
- Key inflammatory cytokines showed increased expression, while important tight junction molecules and keratins decreased, indicating a complex relationship between infection and intestinal barrier dysfunction.