Combined plasma lens and rephasing stage for a laser wakefield accelerator.

Electrons from a laser wakefield accelerator have a limited energy gain due to dephasing and are prone to emittance growth, causing a large divergence. In this paper, we experimentally show that adjusting the plasma density profile can address both issues. Shock-assisted ionisation injection is used to produce 100 MeV quasi-monoenergetic electron bunches in the primary part of the accelerator.

Development of Ultra-High Dose-Rate (FLASH) Particle Therapy.

Research efforts in FLASH radiotherapy have increased at an accelerated pace recently. FLASH radiotherapy involves ultra-high dose rates and has shown to reduce toxicity to normal tissue while maintaining tumor response in pre-clinical studies when compared to conventional dose rate radiotherapy. The goal of this review is to summarize the studies performed to-date with proton, electron, and heavy ion FLASH radiotherapy, with particular emphasis on the physical aspects of each study and the advantages and disadvantages of each modality.

A focused very high energy electron beam for fractionated stereotactic radiotherapy.

An electron beam of very high energy (50-250 MeV) can potentially produce a more favourable radiotherapy dose distribution compared to a state-of-the-art photon based radiotherapy technique. To produce an electron beam of sufficiently high energy to allow for a long penetration depth (several cm), very large accelerating structures are needed when using conventional radio-frequency technology, which may not be possible due to economical or spatial constraints. In this paper, we show transport and focusing of laser wakefield accelerated electron beams with a maximum energy of 160 MeV using electromagnetic quadrupole magnets in a point-to-point imaging configuration, yielding a spatial uncertainty of less than 0.

Laser wakefield accelerated electron beams and betatron radiation from multijet gas targets.

Laser Plasma Wakefield Accelerated (LWFA) electron beams and efficiency of betatron X-ray sources is studied using laser micromachined supersonic gas jet nozzle arrays. Separate sections of the target are used for the injection, acceleration and enhancement of electron oscillation. In this report, we present the results of LWFA and X-ray generation using dynamic gas density grid built by shock-waves of colliding jets.

Author Correction: Laser-wakefield accelerators for high-resolution X-ray imaging of complex microstructures.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Single-Shot Multi-keV X-Ray Absorption Spectroscopy Using an Ultrashort Laser-Wakefield Accelerator Source.

Single-shot absorption measurements have been performed using the multi-keV x rays generated by a laser-wakefield accelerator. A 200 TW laser was used to drive a laser-wakefield accelerator in a mode which produced broadband electron beams with a maximum energy above 1 GeV and a broad divergence of ≈15  mrad FWHM. Betatron oscillations of these electrons generated 1.

Laser-wakefield accelerators for high-resolution X-ray imaging of complex microstructures.

Laser-wakefield accelerators (LWFAs) are high acceleration-gradient plasma-based particle accelerators capable of producing ultra-relativistic electron beams. Within the strong focusing fields of the wakefield, accelerated electrons undergo betatron oscillations, emitting a bright pulse of X-rays with a micrometer-scale source size that may be used for imaging applications. Non-destructive X-ray phase contrast imaging and tomography of heterogeneous materials can provide insight into their processing, structure, and performance.

Optimization of soft X-ray phase-contrast tomography using a laser wakefield accelerator.

X-ray phase-contrast imaging allows for non-invasive analysis in low-absorbing materials, such as soft tissue. Its application in medical or materials science has yet to be realized on a wider scale due to the requirements on the X-ray source, demanding high flux and small source size. Laser wakefield accelerators generate betatron X-rays fulfilling these criteria and can be suitable sources for phase-contrast imaging.

Stable femtosecond X-rays with tunable polarization from a laser-driven accelerator.

Technology based on high-peak-power lasers has the potential to provide compact and intense radiation sources for a wide range of innovative applications. In particular, electrons that are accelerated in the wakefield of an intense laser pulse oscillate around the propagation axis and emit X-rays. This betatron source, which essentially reproduces the principle of a synchrotron at the millimeter scale, provides bright radiation with femtosecond duration and high spatial coherence.

A tunable electron beam source using trapping of electrons in a density down-ramp in laser wakefield acceleration.

One challenge in the development of laser wakefield accelerators is to demonstrate sufficient control and reproducibility of the parameters of the generated bunches of accelerated electrons. Here we report on a numerical study, where we demonstrate that trapping using density down-ramps allows for tuning of several electron bunch parameters by varying the properties of the density down-ramp. We show that the electron bunch length is determined by the difference in density before and after the ramp.

Highly efficient angularly resolving x-ray spectrometer optimized for absorption measurements with collimated sources.

Highly collimated betatron radiation from a laser wakefield accelerator is a promising tool for spectroscopic measurements. Therefore, there is a requirement to create spectrometers suited to the unique properties of such a source. We demonstrate a spectrometer which achieves an energy resolution of <5 eV at 9 keV (E∕ΔE>1800) and is angularly resolving the x-ray emission allowing the reference and spectrum to be recorded at the same time.

Shock assisted ionization injection in laser-plasma accelerators.

Ionization injection is a simple and efficient method to trap an electron beam in a laser plasma accelerator. Yet, because of a long injection length, this injection technique leads generally to the production of large energy spread electron beams. Here, we propose to use a shock front transition to localize the injection.

Experimental measurements of electron-bunch trains in a laser-plasma accelerator.

Spectral measurements of visible coherent transition radiation produced by a laser-plasma-accelerated electron beam are reported. The significant periodic modulations that are observed in the spectrum result from the interference of transition radiation produced by multiple bunches of electrons. A Fourier analysis of the spectral interference fringes reveals that electrons are injected and accelerated in multiple plasma wave periods, up to at least 10 periods behind the laser pulse.

Comparison of measured with calculated dose distribution from a 120-MeV electron beam from a laser-plasma accelerator.

Purpose: To evaluate the dose distribution of a 120-MeV laser-plasma accelerated electron beam which may be of potential interest for high-energy electron radiation therapy.

Methods: In the interaction between an intense laser pulse and a helium gas jet, a well collimated electron beam with very high energy is produced. A secondary laser beam is used to optically control and to tune the electron beam energy and charge.

Mapping the x-ray emission region in a laser-plasma accelerator.

The x-ray emission in laser-plasma accelerators can be a powerful tool to understand the physics of relativistic laser-plasma interaction. It is shown here that the mapping of betatron x-ray radiation can be obtained from the x-ray beam profile when an aperture mask is positioned just beyond the end of the emission region. The influence of the plasma density on the position and the longitudinal profile of the x-ray emission is investigated and compared to particle-in-cell simulations.

Laser-driven plasma waves in capillary tubes.

The excitation of plasma waves over a length of up to 8 cm is demonstrated using laser guiding of intense laser pulses through hydrogen-filled glass capillary tubes. The plasma waves are diagnosed by spectral analysis of the transmitted laser radiation. The dependence of the spectral redshift-measured as a function of filling pressure, capillary tube length, and incident laser energy-is in excellent agreement with simulation results.

Radiochromic film imaging spectroscopy of laser-accelerated proton beams.

This article reports on an experimental method to fully reconstruct laser-accelerated proton beam parameters called radiochromic film imaging spectroscopy (RIS). RIS allows for the characterization of proton beams concerning real and virtual source size, envelope- and microdivergence, normalized transverse emittance, phase space, and proton spectrum. This technique requires particular targets and a high resolution proton detector.

Guiding of relativistic electron beams in solid targets by resistively controlled magnetic fields.

Guided transport of a relativistic electron beam in solid is achieved experimentally by exploiting the strong magnetic fields created at the interface of two metals of different electrical resistivities. This is of substantial relevance to the Fast Ignitor approach to fusion energy production [M. Tabak, Phys.

Active manipulation of the spatial energy distribution of laser-accelerated proton beams.

The spatial energy distributions of beams of protons accelerated by ultrahigh intensity (>10(19)Wcm2) picosecond laser pulse interactions with thin foil targets are investigated. Using separate, low intensity (<10(13)Wcm2) nanosecond laser pulses, focused onto the front surface of the target foil prior to the arrival of the high intensity pulse, it is demonstrated that the proton beam profile can be actively manipulated. In particular, results obtained with an annular intensity distribution at the focus of the low intensity beam are presented, showing smooth proton beams with a sharp circular boundary at all energies, which represents a significant improvement in the beam quality compared to irradiation with the picosecond beam alone.

Influence of shock waves on laser-driven proton acceleration.

The influence of shock waves, driven by amplified spontaneous emission (ASE), on laser-accelerated proton beams is investigated. A local deformation, produced by a cold shock wave launched by the ablation pressure of the ASE pedestal, can under oblique laser irradiation significantly direct the proton beam toward the laser axis. This can be understood in the frame of target normal sheath acceleration as proton emission from an area of the target where the local target normal is shifted toward the laser axis.

Quantitative study of 10 Hz operation of a soft x-ray laser-energy stability and target considerations.

A soft x-ray laser from Ni-like Mo, pumped in grazing incidence (GRIP), is analyzed with regard to high repetition rate operation. Reliable lasing is obtained, but with significant energy fluctuations attributed mainly to beam pointing jitter from the pump laser. Two modes of operation are compared: continuously moving target and stationary target.

Lateral electron transport in high-intensity laser-irradiated foils diagnosed by ion emission.

An experimental investigation of lateral electron transport in thin metallic foil targets irradiated by ultraintense (>or=10(19) W/cm2) laser pulses is reported. Two-dimensional spatially resolved ion emission measurements are used to quantify electric-field generation resulting from electron transport. The measurement of large electric fields ( approximately 0.

Optimization toward a high-average-brightness soft-x-ray laser pumped at grazing incidence.

We report the near-field imaging characterization of a 10 Hz Ni-like 18.9 nm molybdenum soft-x-ray laser pumped in a grazing incidence pumping (GRIP) geometry with a table-top laser driver. We investigate the effect of varying the GRIP angle on the spatial behavior of the soft-x-ray laser source.

Laser-wakefield acceleration of monoenergetic electron beams in the first plasma-wave period.

Beam profile measurements of laser-wakefield accelerated electron bunches reveal that in the monoenergetic regime the electrons are injected and accelerated at the back of the first period of the plasma wave. With pulse durations ctau >or= lambda(p), we observe an elliptical beam profile with the axis of the ellipse parallel to the axis of the laser polarization. This increase in divergence in the laser polarization direction indicates that the electrons are accelerated within the laser pulse.