Changes in neurotransmitter parameters in the brain induced by L-cysteine injections in the young rat.

A single subcutaneous injection of L-cysteine (1.2 mg/g body wt.) to 4-day-old rats leads to atrophy of the brains examined 27-31 days later.

Congestive heart failure and ejection fraction in acute myocardial infarction.

Left ventricular ejection fraction (EF) was determined by means of radionuclide ventriculography (RNV) in 477 patients 8-12 days after an acute myocardial infarction (AMI). EF was correlated to infarct size and clinical and radiological parameters of congestive heart failure (CHF). The 138 patients (29%) who had signs of CHF had a mean (+/- SD) EF of 35 +/- 14% and a relative heart volume of 597 +/- 112 ml/m2 compared to 51 +/- 14% and 487 +/- 88 ml/m2 among those without CHF.

Cardiac performance in hyperthyroidism assessed by systolic time intervals and radionuclide ventriculography.

Systolic time intervals (STI) and radionuclide ventriculography (RNV) were used in the assessment of cardiac performance in 22 patients with hyperthyroidism before and after antithyroid treatment. STI as well as RNV showed enhanced myocardial contractility which was normalized after antithyroid treatment. Beta-blocker treatment did not influence the hypercontractility in hyperthyroidism.

Regional distribution of perchloric acid soluble proteins during the development of rat brain.

The regional contents of perchloric acid (PCA)-soluble proteins were determined during the development of rat brain. The soluble proteins in cortex, mesencephalon and medulla oblongata decreased gradually to adult age, whereas the levels in cerebellum increased significantly 12 days after birth followed by a decline to adult age. The developmental changes in the soluble proteins in retina, which showed the highest content of these proteins, were different from that of the other regions.

Combined scintigraphy of liver, spleen, and lung in the diagnosis of subphrenic abscess.

Two hundred and fifty-six patients have, during the past 5 years, been examined by combined liver, spleen, and lung radionuclide imaging. The reason for this investigation was to identify or rule out subphrenic abscess, which is a rare but feared complication of abdominal surgery. Primary subphrenic abscess may also be seen, and in such cases the diagnosis is extremely difficult.