Publications by authors named "Luna L van der Gun"
Article Synopsis
- The study investigates how gut microbiota from patients with anorexia nervosa (AN) affects anxiety, cognitive flexibility, and dopamine signaling in rats through fecal microbiota transplantation (FMT).
- Results showed no significant changes in cognition or dopamine activity after receiving microbiota from AN patients compared to controls, although antibiotic treatment lowered task engagement in the rats.
- The findings suggest that while AN-associated gut microbiota may not directly influence cognitive flexibility, the limitations of the FMT methods used indicate a need for better experimental protocols in future research.
Purpose Of Review: We are currently in the midst of a global opioid epidemic. Opioids affect many physiological processes, but one side effect that is not often taken into consideration is the opioid-induced alteration in blood glucose levels.
Recent Findings: This review shows that the vast majority of studies report that opioid stimulation increases blood glucose levels.
Opioids are known to affect blood glucose levels but their exact role in the physiological control of glucose metabolism remains unclear. Although there are numerous studies investigating the peripheral effects of opioid stimulation, little is known about how central opioids control blood glucose and which brain areas are involved. One brain area possibly involved is the nucleus accumbens because, as well as being a key site for opioid effects on food intake, it has also been implicated in the control of blood glucose levels.
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