Mild Synovitis Impairs Chondrogenic Joint Environment.

The impact of mild synovitis on the chondrogenic environment in the joint pertaining to cartilage repair is often neglected. In this study, 21 synovial samples were collected from foot surgeries for histology and isolation of fibroblast-like synoviocytes (FLSs). Of the 21 samples, 13 were normal and eight were mild synovitis, according to their synovitis scores.

Increased synovial expression of calcitonin gene-related peptide and its potential roles in Charcot Neuroarthropathy.

Objective: Joint destruction in Charcot neuroarthropathy (CNA) is accompanied with abundant hyperplastic synovium. This study aimed to characterize the expression patterns of a group of neuropeptides in the CNA synovium.

Methods: Synovial specimens were collected during surgery from the CNA (n = 6) and non-CNA joints (n = 14).

Expression profile of matrix metalloproteinases in the labrum of femoroacetabular impingement.

Aims: Femoroacetabular impingement (FAI) is a potential cause of hip osteoarthritis (OA). The purpose of this study was to investigate the expression profile of matrix metalloproteinases (MMPs) in the labral tissue with FAI pathology.

Methods: In this study, labral tissues were collected from four FAI patients arthroscopically and from three normal hips of deceased donors.

Orthotopic Transplantation of Achilles Tendon Allograft in Rats: With or without Incorporation of Autologous Mesenchymal Stem Cells.

The biology and function of orthotopic transplantation of Achilles tendon allograft are unknown. Particularly, the revitalization of Achilles allograft is a clinical concern. Achilles allografts were harvested from donor rats and stored at -80 °C.