Screening and Experimental Validation of Novel MexAB-OprM Efflux Pump Inhibitors of .

The emergence of multidrug-resistant possesses a significant public health concern. Constitutively expressed MexAB-OprM efflux pumps in significantly contribute to its resistance to a variety of antibiotics. The development of efflux pump inhibitors (EPIs) has emerged as an attractive strategy in reversing antibiotic resistance.