The diagnostic performance of T1 mapping in the assessment of breast lesions: A preliminary study.

Purpose: To assess T1 mapping performance in distinguishing between benign and malignant breast lesions and to explore its correlation with histopathologic features in breast cancer.

Methods: This study prospectively enrolled 103 participants with a total of 108 lesions, including 25 benign and 83 malignant lesions. T1 mapping, diffusion-weighted imaging (DWI), and dynamic contrast-enhanced (DCE) were performed.

Risk factors for acute kidney injury and kidney relapse in patients with lupus podocytopathy.

Background: Patients with lupus podocytopathy show a high incidence of acute kidney injury (AKI) and relapse, but the risk factors and mechanisms were unclear. This study analysed the clinicopathological features and risk factors for AKI and relapse in lupus podocytopathy patients.

Methods: The cohort of lupus podocytopathy was generated by screening the biopsies of patients with lupus nephritis (LN) from 2002 to 2022 and was divided into the mild glomerular lesion (MGL) and focal segmental glomerulosclerosis (FSGS) groups based on glomerular morphological characteristics.

Case report: [F]FAPI-42 PET/CT visualize primary adenoid cystic carcinoma not detected by [F]FDG.

Adenoid cystic carcinoma (ACC) is a rare salivary gland cancer. Still, its growth and invasion progress is slow, and its hematogenous metastasis is ACC's most common distant metastasis. Because of the broad expression and low background uptake of fibroblast activation protein (FAP) in tumor stroma, FAPI is considered another potential tracer of ACC in addition to FDG.

Breast-lesion assessment using amide proton transfer-weighted imaging and dynamic contrast-enhanced MR imaging.

Background: Previous studies have indicated that amide proton transfer-weighted imaging (APTWI) could be utilized for differentiating benign and malignant tumors. The APTWI technology has increasingly being applied to breast tumor research in recent years. However, according to the latest literature retrieval, no relevant previous studies compared the value of APTWI and dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) in distinguishing benign lesions from malignant lesions.

MCC Regulator of WNT Signaling Pathway (MCC) Is a Podocyte Essential Gene.

Podocytes are an integral part of the glomerular filtration barrier. Many genes are already known to be essential for podocyte survival, structure and function, but there are more podocyte essential genes to be identified. By single-cell RNA-seq of mouse podocytes, we detected the expression of gene encoding MCC regulator of WNT signaling pathway (MCC) in majority of the podocytes and speculated that MCC is essential for podocytes.

In-situ reduction of monodisperse nanosilver on hierarchical wrinkled mesoporous silica with radial pore channels and its antibacterial performance.

Monodisperse silver nanoparticles (Ag NPs) were facilely loaded on the inner and outer surface of hierarchical wrinkled mesoporous silica (WMSs) via an in situ chemical reduction, and the antibacterial capacity of the obtained nanocomposite was investigated in detail. Typical sulfydryl-functionalized wrinkled mesoporous silica nanoparticle with radical pore channels was firstly prepared through sol-gel technique with cetyltrimethylammonium bromide (CTAB) as the templating surfactant. After sulfonation of the as-prepared WMSs, Ag(+) ions were then densely locked up on the inner and outer surface of WMSs via electrostatic interactions.