Publications by authors named "Lulu Xin"
To evaluate the impact of perioperative comprehensive nursing intervention on postoperative urinary incontinence, various aspects of patient well-being were assessed. The comprehensive group, that received the nursing intervention, demonstrated significant improvements in self-care skills, health knowledge level, self-care responsibility, and self-concept compared to the standard group. The findings indicate that perioperative comprehensive nursing intervention has a remarkable effect on patients undergoing laparoscopic radical prostatectomy.
View Article and Find Full Text PDFNovel mechanism of hydrogen peroxide for promoting efficient natamycin synthesis in .
Microbiol Spectr
September 2023
Article Synopsis
- The study investigates how oxidative stress controls natamycin production in Streptomyces, revealing that cholesterol oxidase SgnE plays a crucial role in this process.
- It demonstrates that the enzyme SgnE produces hydroxycholesterol (HO), which initiates a cascade of redox-dependent interactions that regulate the expression of genes involved in natamycin biosynthesis.
- The protein OxyR acts as a redox switch, working with another regulator, SgnR, to adjust the transcription of natamycin-related genes depending on the oxidative state, ultimately providing insights for enhancing antibiotic production by managing intracellular redox levels.
Streptomyces gilvosporeus F607 produces large amounts of natamycin in a process regulated by multiple networks, including two-component systems (TCSs). The macR and macS genes, which are annotated as rs12540 and rs12545, respectively, in S. gilvosporeus F607, affect natamycin biosynthesis and sporulation.
View Article and Find Full Text PDF